Azoles
Medchemexpress LLC Acoramidis hydrochloride | 2242751-53-5 | 98.5% | 328.77 | 10 MG
Acoramidis hydrochloride | 2242751-53-5 | 98.5% | 328.77 | 10 MG
Medchemexpress LLC 2-Pyrrolidinone, 5-[(3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]- | 346673-06-1 | 98.3% | 383.49 | 50 MG
TCS 2510 is a selective EP4 agonist and can be used for the research of metabolic diseases. It stimulates glucagon-like peptide 1 and 2 secretion, activates the Gas signaling pathway, and increases Gcg mRNA expression levels. In vivo studies show it elevates plasma glucagon-like peptide 1 and 2 levels in mice.
- Stimulates glucagon-like peptide 1 secretion.
- Activates the Gas signaling pathway.
- Increases Gcg mRNA expression levels.
- Produces a concentration-dependent increase in cAMP levels in GLUTag cells.
- Decreases cell impedance in GLUTag cells.
- Produces a concentration-dependent increase in glucagon-like peptide 2 secretion.
- Elevates plasma glucagon-like peptide 1 levels in fasted mice.
- Increases plasma glucagon-like peptide 2 levels in mice.
Medchemexpress LLC Methyl L-pyroglutamate | 4931-66-2 | 99.6% | 143.14 | 10 G
Methyl L-pyroglutamate is isolated from *P. oleracea* and has anti-inflammatory activity. It is also known as (S)-Methyl 5-oxopyrrolidine-2-carboxylate or L-Pyroglutamic acid methyl ester.
- Exhibits anti-inflammatory activity
- Provided as a colorless to light yellow liquid
- High purity of 99.62%
- Suitable for in vitro and in vivo studies with various dissolution protocols
Medchemexpress LLC Methyl L-pyroglutamate | 4931-66-2 | 99.62% | 143.14 | 1 ML
Methyl L-pyroglutamate, isolated from P. oleracea, exhibits anti-inflammatory activity and is intended for research use only.
- Anti-inflammatory activity
- Isolated from P. oleracea
- For research use only
Medchemexpress LLC M-89 | 2363165-42-6 | 99.1% | 10 MG
M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to study MLL leukemia. M-89 inhibits the cell growth in leukemia cell lines carrying MLL fusion.
- Inhibits the cell growth of MV4-11 cell line with an IC50 of 25 nM.
- Inhibits the cell growth of HL-60 cell line with an IC50 of 10.2 μM.
- Stabilized the cellular menin protein in both MV4-11 and MOLM-13 cells dose-dependently (3.7-300 nM).
- Induces a time- and dose-dependent apoptosis in MV4-11 cells (0.03-3 μM, 48 h).
Medchemexpress LLC 2'3'-c-di-AM(PS)2 (Rp,Rp) enantiomer (ammonium salt) | 98.9% | 10 MG
2'3'-c-di-AM(PS)2 (Rp,Rp) enantiomer ammonium salt is the less active enantiomer of 2'3'-c-di-AM(PS)2 (Rp,Rp), an activator of stimulator of interferon genes (STING). This chemical is intended for laboratory research and manufacture of substances.
- Appearance: Solid
- Color: White to off-white
- Molecular weight: 724.60
- Formula: C20H30N12O10P2S2
- Purity: 98.9%
- Solubility in water: ≥ 100 mg/mL
- Solubility in DMSO: 50 mg/mL
- Recommended storage for solid: -20°C, sealed, away from moisture and light.
Medchemexpress LLC Dimethyl methylene blue zinc chloride double salt | 931418-92-7 | MFCD19686959 | 99.6% | 416.04 | C18H22N3S·1/2ZnCl4 | 250mg
Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin releasing DMMB and increasing the fluorescence intensity Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E Coli) endotoxin[1]
eMolecules NH-bis(PEG4-OH) | 63721-06-2 | MFCD30536158 | 1g
Broadpharm | NH-bis(PEG4-OH) | 1g | 336613479 | BP-23439 | 98.000 | 63721-06-2 | MFCD30536158 | 457.561 | C20H43NO10
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Medchemexpress LLC Pomalidomide-5-C11-NH2 hydrochloride | 98.2% | 479.01 g/mol | C24H35ClN4O4 | 10 MG
Pomalidomide-5-C11-NH2 hydrochloride is a pomalidomide-based cereblon (CRBN) ligand used to recruit the CRBN E3 ligase in targeted protein degradation studies and other chemical biology applications. Supplied as the hydrochloride salt, the compound is provided as a light blue to blue solid with high reported purity and is packaged in small milligram quantities for research use. Storage and handling instructions are provided to preserve stability.
- High purity (98.2%) suitable for research-grade applications.
- Hydrochloride salt form for improved stability and handling.
- Light blue to blue solid for straightforward visual identification.
- Available in small milligram packaging for screening and synthesis workflows.
- Storage guidance provided to maintain compound integrity.
Medchemexpress LLC Allopurinol (Standard) | 315-30-0 | 99.9% | 50 MG
Allopurinol (Standard) is the analytical standard of Allopurinol, intended for research and analytical applications. It is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It can be used in the research of hyperuricemia and gout, and also decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant, anti-nociception activity, and anti-leishmanial effect. The compound is a reference standard supplied for assay and is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Allopurinol
- Potent and orally active xanthine oxidase inhibitor
- Used in research of hyperuricemia and gout
- Decreases expression of HIF-1α and HIF-2α protein
- Shows anti-depressant and anti-nociception activity
- Anti-leishmanial effect
- Commonly used in HPLC, GC, and MS experiments