Phthalazinone pyrazole is a potent, selective, orally active small-molecule inhibitor of Aurora-A kinase used for research in cell biology and oncology. It has a biochemical IC50 of 0.031 μM against Aurora-A and shows cellular activity in multiple cancer cell lines.
- Potent Aurora-A kinase inhibition (IC50 0.031 μM).
- Demonstrated cellular activity in COLO 205, HCT-116, and MCF7 cell lines.
- High purity suitable for research (98.0%).
- Well-characterized physicochemical properties (C18H15N5O; MW 317.34).
- Available as solid and solution formats for assay flexibility.
- Supplied with a datasheet containing analytical and handling information.