2'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt, also known as ADU-S100 disodium salt, is a potent activator of stimulator of interferon genes (STING). This compound is utilized in research related to inflammation, immunology, and cancer studies.
- Activates all five human STING alleles.
- Induces high expression of IFN-β and pro-inflammatory cytokines.
- Shows enhanced type I interferon production.
- Demonstrates higher anti-tumor control compared to endogenous ML cGAMP.
- Improves long-term survival in tumor models.