Azoles
Medchemexpress LLC 3-fluorobutan-1-amine hydrochloride | 1780799-10-1 | MFCD28538986 | 95.0% | 127.59 g/mol | C4H11ClFN | 100 MG
3-fluorobutan-1-amine hydrochloride is a fluorinated primary amine supplied as the hydrochloride salt and used as a chemical intermediate for the synthesis of active organic compounds.
- Primary amine hydrochloride salt.
- Fluorinated C4 building block for synthesis.
- CAS number 1780799-10-1.
- Molecular weight 127.59 g/mol.
- Purity 95.0% (as reported on certificate of analysis).
- Solid; store sealed at room temperature, away from moisture and light.
- Commonly supplied in small laboratory pack sizes such as 100 mg.
Apexbio Technology LLC TH-302 918633-87-1 10mg
TH-302 (CAS 918633-87-1) is a hypoxia-activated prodrug comprising a 2-nitroimidazole moiety linked to a brominated isophosphoramide mustard Under severe hypoxic conditions (approximately 0 1% O ) TH-302 undergoes bioreductive activation releasing the cytotoxic alkylating agent Br-IPM selectively within hypoxic tumor microenvironments In vitro studies demonstrate markedly increased cytotoxicity against tumor cell lines under hypoxia with IC50 values ranging from 0 1 to 0 8 M for H460 Caki-1 SK-MEL-5 DU145 and HCT116 cells while IC50 values exceed 40 M in normoxic conditions In H460 xenograft mouse models TH-302 induces dose-dependent tumor growth inhibition without hematological toxicity and increases H2AX-positive cells indicating DNA damage TH-302 is utilized to investigate tumor hypoxia-targeting therapies and mechanisms of selective cytotoxicity
Medchemexpress LLC Palmitoleoyl chlorid 50mg | 40426-22-0 | 272.85 g/mol | C16H29ClO | 50 MG
Palmitoleoyl chloride is an acyl chloride derivative of palmitoleic acid used as a reactive intermediate in organic and medicinal chemistry. Supplied for research use, it is commonly used to introduce a palmitoleoyl (C16:1) acyl group into target molecules.
- Purity 95.0%.
- Chemical formula C16H29ClO; molecular weight 272.85 g/mol.
- Appearance: light yellow to brown liquid.
- Soluble in DMSO (≈50 mg/mL; may require ultrasonic).
- Storage: recommended -20°C for long-term storage; additional guidance for solutions applies.
- Intended for research use only.
![Medchemexpress LLC (2S,4R)-1-[(2S)-2-[(1-cyanocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy | 2097381-85-4 | MFCD30742947 | >98.0% | 523.65 g/mol | C27H33N5O4S | 2 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211825.png-250.jpg)
Medchemexpress LLC (2S,4R)-1-[(2S)-2-[(1-cyanocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy | 2097381-85-4 | MFCD30742947 | >98.0% | 523.65 g/mol | C27H33N5O4S | 2 MG
VH-298 is a potent, cell-permeable small molecule that inhibits the VHL:HIF-α protein-protein interaction, stabilizing HIF-α and inducing a hypoxic response in cells. It is commonly used as a chemical probe and as an E3 ligase ligand in the design of PROTACs for cell-based studies.
- High binding affinity (Kd ≈ 80-90 nM).
- Cell-permeable and reported non-toxic in cellular assays.
- Induces HIF-α accumulation in treated cells.
- Useful as an E3 ligase ligand for PROTAC construction.
- Supplied as a small-molecule solid suitable for synthesis and biological assays.
Medchemexpress LLC 2-Hydroxy-4-methylth 10mM 1mL | 583-91-5 | 150.20 | C5H10O3S | 1 ML
2-Hydroxy-4-(methylthio)butyric acid is an organic acid used as an orally active source of methionine for research applications. Supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and in larger liquid quantities, it is used in studies of methylation, nutrient supplementation, and lactation.
- Ready-to-use 10 mM solution in DMSO (1 mL) for convenient dosing.
- Available in bulk liquid quantities for formulation and scale-up.
- Modulates expression of methylation-related mRNAs such as BHMT, MTR, MAT1A, SAHH, and PCK1.
- Serves as an orally active methionine precursor for nutritional and physiological studies.
- Identified by CAS 583-91-5; molecular weight 150.20; formula C5H10O3S.
Medchemexpress LLC tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | 99.97% | 278.36 | 10 G
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only. This product is a solid, with a color ranging from white to yellow.
- Used in the synthesis of active compounds
- Suitable for research applications
- Available as a white to yellow solid
- Should be stored away from moisture and light
Medchemexpress LLC Methyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate | 179003-02-2 | 279.34 | 250 MG
Methyl 3-(2-((tert-butoxycarbonyl)amino)ethyl)benzoate is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and should be handled by suitably qualified, experienced personnel in appropriately equipped facilities.
- Used as a drug intermediate.
- Suitable for synthesis of various active compounds.
- Identified for laboratory chemical use.
- Intended for manufacture of substances.
- For research use only.