(S,R,S)-AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that couples the (S,R,S)-AHPC VHL ligand to a 10-carbon alkyl linker. It is designed for use as the VHL-recruiting element in BET-targeted PROTAC design and for studies involving E3 ligase ligand conjugation.
- Provides a VHL-based E3 ligase recruiting moiety for PROTAC development.
- Contains a 10-carbon alkyl linker to provide spacer flexibility between ligand and target binder.
- Designed for chemical synthesis and linker conjugation chemistry.
- Characterized by molecular formula C38H59N5O6S and molar mass 713.97 g·mol⁻¹.
- Store sealed away from moisture and light; in solvent: -80°C up to 6 months, -20°C up to 1 month.