Azoles
![Apexbio Technology LLC Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096433.png-250.jpg)
Apexbio Technology LLC Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] 5mg
Cytochrome P450 CYP1B1 190-198 is a tumor-associated antigen peptide derived from CYP1B1 It is designed to induce HLA-A2-restricted T-cell responses against the CYP1B1(190-198) epitope thereby promoting tumor-specific cytotoxic immune responses Cytochrome P450 CYP1B1 190-198 exerts its biological activity primarily through antigen-specific activation of CD8 T cells In HLA-A2 transgenic mouse models this peptide delivered via plasmid DNA and poly(lactide-co-glycolide) microparticles demonstrates the ability to elicit CYP1B1 peptide-specific T-cell immunity Based on these pharmacological properties Cytochrome P450 CYP1B1 190-198 holds research potential in cancer immunotherapy and studies of tumor-specific cytotoxic T-cell responses
![eMolecules 344361-90-6 | ETHYL 4-METHYL-2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBOXYLATE | AstaTech | MFCD19442787 | 228.270 | C9H12N2O3S | 95.000 | CCOC(=O)c1c(C)nc(SC)[nH]c1=O | 1g | 384830780](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502178543.JPG-250.jpg)
eMolecules 344361-90-6 | ETHYL 4-METHYL-2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBOXYLATE | AstaTech | MFCD19442787 | 228.270 | C9H12N2O3S | 95.000 | CCOC(=O)c1c(C)nc(SC)[nH]c1=O | 1g | 384830780
ETHYL 4-METHYL-2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBOXYLATE | AstaTech | 344361-90-6 | MFCD19442787 | 228.270 | C9H12N2O3S | 95.000 | CCOC(=O)c1c(C)nc(SC)[nH]c1=O | 1g | 384830780
Medchemexpress LLC BAY-298 | 2471978-97-7 | 99.9% | 10 MM * 1 ML
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It demonstrates potent activity against human, rat, and cynomolgus monkey LH receptors, effectively reducing sex hormone levels. It is supplied as a 10 MM solution in DMSO.
- Orally active and selective LH-R antagonist
- Reduces sex hormone levels
- Potent inhibitory activity against human, rat, and cynomolgus monkey LH receptors
- Inhibits human ERG in HEK293 cells
- Lowers serum estradiol levels in proestrus female rats
Medchemexpress LLC Imidazo[1,2-a]pyrazine, 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- | 3023925-68-7 | C25H26N6O | 50 MG
YL-939 is a potent ferroptosis inhibitor that targets the PHB2/ferritin/iron axis. It efficiently protects cells from ferroptosis and has shown to ameliorate liver damage in an Acetaminophen (APAP)-induced acute liver injury model.
- Potent ferroptosis inhibitor
- Targets the PHB2/ferritin/iron axis
- Protects cells from ferroptosis
- Reduces ROS levels in cytosolic and membrane lipids
- Inhibits ferritinophagy by improving ferritin protein expression
- Ameliorates liver damage in APAP-induced acute liver injury models
- High purity of 99.03%
- Solid appearance, off-white to light yellow color
eMolecules 58304-65-7 | AstaTech | 1-CHLORO-2-METHYLPROPYL PROPIONATE | 1g | 233619311 | 25803 | 95 | MFCD09033184 | 164.63 | C7H13ClO2
AstaTech | 1-CHLORO-2-METHYLPROPYL PROPIONATE | 1g | 233619311 | 25803 | 95.000 | 58304-65-7 | MFCD09033184 | 164.630 | C7H13ClO2
Medchemexpress LLC Met kinase-IN-2 | 2101241-90-9 | 98.4% | 562.59 g/mol | C33H27FN4O4 | 5 MG
MET kinase-IN-2 is a potent, selective MET (c-Met/HGFR) kinase inhibitor with an enzymatic IC50 of 7.4 nM. The compound shows cellular growth inhibition across multiple cancer cell lines and demonstrates oral antitumor efficacy in xenograft models. It is supplied for preclinical research and is well characterized for purity and molecular properties.
- Potent MET kinase inhibition (IC50 7.4 nM).
- Selective profile with additional activity against AXL, Flt4, KDR, Mer, TEK, and TYRO3.
- Orally bioavailable with demonstrated in vivo antitumor efficacy.
- Documented cellular activity in multiple cancer cell lines.
- High purity and characterized molecular weight and formula.
Medchemexpress LLC N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide | 2244678-29-1 | 98.4% | 50 MG
TH-257 (CAS 2244678-29-1) is a small-molecule allosteric inhibitor of LIM kinase 1 and 2 used as a biochemical research probe to study LIMK-mediated signaling pathways in vitro.
- Potent inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM.
- Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.
- High purity (98.36%) suitable for in vitro biochemical studies.
- Supplied as a solid powder and as a 10 mM solution in DMSO; common pack sizes include 5 mg, 10 mg, 50 mg, and 100 mg.
Selleck Chemical LLC (R)-Nepicastat HCl S4926-10mg
(R)-Nepicastat HCl (RS-25560-198) the R-enantiomer of Nepicastat HCl is a potent and selective inhibitor with IC50 of 25 1 nM and 18 3 nM for bovine and human dopamine- -hydroxylase with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors
Aobchem 4-Bromo-2-chlorothiazole | ≥95% | CAS 92977-45-2 | C3HBrClNS | 250mg
4-Bromo-2-chlorothiazole | ≥95% | CAS 92977-45-2 | C3HBrClNS | 250mg
Aobchem 5-Bromo-2-chlorothiazole | ≥95% | CAS 3034-56-8 | C3HBrClNS | 25g
5-Bromo-2-chlorothiazole | ≥95% | CAS 3034-56-8 | C3HBrClNS | 25g