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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
A polyphenol with diverse biological activities; active against MRSA at 0.01 UG/ml; prevents hexavalent chromium-induced formation of ROS and NOS in a concentration-dependent manner and increases GSH in isolated human erythrocytes; selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM); inhibits proliferation of HT-29 cells at 362 µM but not HCT116 cells at 100 µM
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Antitumor agent-127 (compound 1) is a parent macrocyclic peptide that displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines. It does not induce apoptosis in Mia PaCa-2 cells, a model pancreatic tumor cell line with low cell surface expression of ROR1.
Displays nanomolar cell-based binding to ROR1.
Demonstrates good internalization in 786-O and MDA-MB-231 tumor cell lines.
Does not induce apoptosis in Mia PaCa-2 cells.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More