(E)-2-Hexadecenal (trans-2-Hexadecenal) is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. It activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK. This product has potential applications in research related to sphingolipid signaling pathways.
- MLK3 activator
- Induces cytoskeletal remodeling
- Leads to cell rounding, detachment, and apoptosis
- Activates MLK3 signaling pathway
- Phosphorylates MKK4/7 and JNK
- Activates downstream targets of JNK
- Potential applications in sphingolipid signaling pathway research