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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a cytidine analog. Cytidine analogs inhibit DNA methyltransferases and possess potential anti-metabolic and anti-tumor activities.
Cytidine analog
Inhibits DNA methyltransferases
Possesses anti-metabolic activity
Possesses anti-tumor activity
Nucleoside antimetabolite/analog
Related to oligonucleotides
Related to phosphoramidites
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2'-Deoxy-2'-fluoro-β-D-arabino-6-azauridine is a purine nucleoside analog that primarily targets DNA synthesis pathways. It exhibits broad antitumor activity and is particularly effective against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA replication and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development in oncology.
Primarily targets DNA synthesis pathways.
Exhibits broad antitumor activity.
Effective against indolent lymphoid malignancies.
Inhibits DNA replication.
Induces apoptosis.
Valuable tool for cancer research.
Useful for therapeutic development in oncology.
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3'-Deoxy-3'-fluorouridine is a purine nucleoside analog with a molecular formula of C9H11FN2O5. It appears as a white to off-white solid and has a high purity of 99.66% as determined by LCMS. This product is intended for research use only and has not been fully validated for medical applications.
White to off-white solid appearance
Purity of 99.66% (LCMS)
Consistent with structure based on 1H NMR spectrum and LCMS
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VB124, a potent and selective MCT4 inhibitor, specifically inhibits lactate efflux/import in MDA-MB-231 cells expressing MCT4, and is used for the research of cardiac hypertrophy, heart failure, and metabolism.
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2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a cytidine analog. Cytidine analogs work by inhibiting DNA methyltransferases and show potential anti-metabolic and anti-tumor activities.
Cytidine analog
Inhibits DNA methyltransferases
Shows potential anti-metabolic activities
Shows potential anti-tumor activities
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Oxybenzone-13C6 (Benzophenone 3-13C6) is the 13C-labeled Oxybenzone. It is a widely used UV filter in sun tans and skin protectants that acts as an endocrine-disrupting chemical (EDC) and can traverse the placental and blood-brain barriers. Benzophenone-3 has been shown to impair autophagy, alter epigenetic status, and disrupt retinoid X receptor signaling in apoptotic neuronal cells.
Can be utilized as a tracer.
Can serve as an internal standard for quantitative analysis using methods such as NMR, GC-MS, or LC-MS.
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5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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Bromopyruvic acid (3-Bromopyruvic acid, 3-Bromopyruvate, Bromopyruvic acid, Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs.
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