Carbonyl compounds
Medchemexpress LLC KNT-127 | 1256921-89-7 | 99.6% | 5 MG
KNT-127 is a selective, blood-brain barrier penetrant δ-opioid receptor agonist used in neurological research. It exhibits high affinity for the δ receptor and biased signaling that favors cAMP pathways, with reported effects in preclinical models.
- Selective δ-opioid receptor agonist.
- Blood-brain barrier penetrant for central nervous system studies.
- Biased ligand favoring cAMP signaling over β-arrestin.
- High purity suitable for in vivo and in vitro research applications.
- Available in small-mass packages for dosing flexibility.
Sigma Aldrich Fine Chemicals Biosciences Glutaraldehyde solution Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative | 111-30-8 | MFCD00007025 | 80ML
Glutaraldehyde solution Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative | Mol Wt: 100.12 | 111-30-8 | MFCD00007025 | 80ML
Medchemexpress LLC (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide | 1147883-03-1 | MFCD00824427 | 99.3% | 265.30 g/mol | C14H19NO4 | 50MG
EPI-589 is a redox-active quinone derivative investigated as a neuroprotective small molecule. It acts as an oxidoreductase inhibitor and free radical scavenger, and has demonstrated blood-brain barrier permeability and oral bioavailability in preclinical and early clinical studies. It is used in research on neurodegenerative diseases to study oxidative stress and mitochondrial dysfunction.
- Redox-active oxidoreductase inhibitor and free radical scavenger.
- Blood-brain barrier permeable and orally bioavailable.
- Demonstrated neuroprotective activity in preclinical models.
- High purity suitable for research applications.
- Soluble in DMSO; hygroscopic-use freshly opened solvent.
- Stable as a powder when stored at -20°C or refrigerated per supplier guidance.
Medchemexpress LLC Propranolol hydrochloride | 318-98-9 | 5 G
Propranolol is a nonselective and BBB-permeable β-adrenergic receptor (βAR) antagonist, demonstrating high affinity for β1AR and β2AR. It is utilized in the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.
- Formula: C16H22ClNO2
- Molecular Weight: 295.80
- Appearance: Solid
- Melting/freezing point: 163-165 °C
- For research use only
Sigma Aldrich Fine Chemicals Biosciences Isovaleraldehyde 97 fG
Isovaleraldehyde is one of the flavor compounds identified in wheat corn-grits and tequila.
Sigma Aldrich Fine Chemicals Biosciences Glutaraldehyde solution 50% in H2O, suitable for photographic applications | 111-30-8 | MFCD00007025 | 100ML
Glutaraldehyde solution 50% in H2O, suitable for photographic applications | Mol Wt: 100.12 | 111-30-8 | MFCD00007025 | 100ML
Apexbio Technology LLC Rhodamine 123 (chloride) 62669-70-9 100mg
Rhodamine 123 chloride (CAS 62669-70-9) is a cationic fluorescent dye targeting the mitochondrial membrane potential ( m) It is designed to selectively accumulate within the mitochondrial matrix by crossing the plasma membrane thus enabling detection of mitochondrial function and membrane integrity Rhodamine 123 chloride exerts its biological activity primarily by responding to changes in mitochondrial membrane potential producing yellow-green fluorescence upon accumulation in live-cell mitochondria In cell-based studies its fluorescence intensity directly reflects m but no specific IC50 or EC50 value or experimental cell line is reported Based on these properties Rhodamine 123 chloride holds research potential in measuring mitochondrial function assessing apoptosis evaluating ATP production and monitoring P-glycoprotein-mediated efflux in fluorescence microscopy and flow cytometry applications
Sigma Aldrich Fine Chemicals Biosciences Spermidine BioReagent for25G
Spermidine belongs to the natural polyamines that are found in chloroplasts and in bacterial or eukaryotic cells.
Medchemexpress LLC Beta-D-galactose pentaacetate | 4163-60-4 | MFCD00063259 | 99.6% | 390.34 | C16H22O11 | 1000 G
β-D-Galactose pentaacetate is the peracetylated derivative of beta-D-galactose used as a protected sugar reagent in organic synthesis and biochemical research. Supplied as a high-purity solid for research use.
- Peracetylated monosaccharide useful for glycosylation and derivatization reactions.
- Supplied as a solid with high purity suitable for research applications.
- Molecular formula C16H22O11 and molecular weight 390.34 g/mol.
- Storage: solid under nitrogen at 4°C; in solution store short-term at -20°C to -80°C.
- Available in multiple pack sizes up to 1000 g.
Medchemexpress LLC Octrizole-13C6 | >97.0% | C20H25N3O | 1mg
Octrizole-13C6 is 13C labeled Octrizole[1]
Apexbio Technology LLC HO-3867 1172133-28-6 10mM (in 1mL DMSO)
HO-3867 (CAS 1172133-28-6) is a synthetic curcumin analog that functions as a selective inhibitor of signal transducer and activator of transcription 3 (STAT3) By specifically blocking STAT3 phosphorylation transcriptional activity and DNA binding HO-3867 suppresses the expression of STAT3-mediated genes involved in cellular proliferation and survival without affecting other STAT family members In cell-based studies HO-3867 induces apoptosis in ovarian and endometrial cancer cells while exhibiting minimal cytotoxicity toward nonmalignant cells In vivo HO-3867 reduces tumor growth in xenograft mouse models and inhibits vascular smooth muscle cell proliferation by upregulating PTEN expression This compound is valuable for investigating STAT3-driven oncogenesis and related cellular pathways
Medchemexpress LLC Bis-Tris hydrochlor 10g
Bis-Tris hydrochloride is a biological buffer and can be used in gel electrophoresis separations cell culture and bioprocessing applications[1]
Medchemexpress LLC Knt-127 | 1256921-89-7 | 99.6% | 1 ML
KNT-127 is a selective, brain-penetrant δ-opioid receptor (DOR) agonist supplied as a 10 mM solution in DMSO. It acts as a biased ligand favoring cAMP signaling over β-arrestin pathways and is used in preclinical research on opioid receptor pharmacology and neurological models. Not for human or veterinary use.
- Selective δ-opioid receptor agonist with high potency
- Biased signaling that favors cAMP over β-arrestin pathways
- Supplied as a 10 mM solution in DMSO, 1 mL
- High purity suitable for research (99.6%)
- Molecular formula C24H24N2O2; molecular weight 372.46 g/mol