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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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2-Deoxy-D-glucose 6-phosphate disodium is produced in mammalian cells by the action of hexokinase on 2-DG. It is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
Derivative of 2-Deoxy-D-glucose
Produced in mammalian cells by hexokinase action on 2-DG
Functions as a glucose analog
Acts as a competitive inhibitor of glucose metabolism
Inhibits glycolysis via hexokinase actions
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BAY 80-6946 (Copanlisib CAS number 1032568-63-0) is a small molecule inhibitor targeting class I phosphatidylinositol-3-kinase (PI3K) with potent inhibitory activity against PI3K- and PI3K- isoforms By blocking PI3K enzymatic activity Copanlisib interferes with downstream signaling pathways crucial for cell proliferation and survival In vitro studies demonstrate notable antiproliferative effects in cancer cell lines such as HuCCT-1 and EGI-1 (KRASG12D mutants) exhibiting IC50 values of approximately 147 nM and 137 nM respectively Clinical trials indicate potential utility in treating B-cell malignancies like chronic lymphocytic leukemia and non-Hodgkin lymphoma
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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2'-Deoxy-2'-fluorocytidine is a nucleoside analog that acts as a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. It can work synergistically with T705 to enhance the antiviral effects of both compounds on CCHFV replication.
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6A-azido-6A-deoxy-β-cyclodextrin is a mono-substituted β-cyclodextrin bearing an azide functional group at the 6A position. It is a water-soluble derivative commonly used as a linker in click chemistry for bioconjugation and for host-guest complexation studies.
Contains an azide group for CuAAC and SPAAC click reactions.
High purity (98.0%).
Water-soluble mono-substituted β-cyclodextrin.
Suitable for bioconjugation and host-guest complexation studies.
Solid form for straightforward handling and weighing.
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2'-Deoxy-2'-fluorocytidine is a nucleoside analog that acts as a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. It can also synergistically enhance the antiviral effects of T705 against CCHFV replication.
Potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication.
Acts synergistically with T705 to increase antiviral effects on CCHFV replication.
Available in various quantities and forms: solid, and solutions (e.g., 10 mM * 1 mL in Water).
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