Chlorogenic acid butyl ester, a caffeoylquinic acid, is a potent melanogenesis inhibitor. It inhibits the expression of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosinerelated protein 1 (TRP-1), and TRP-2. This compound also demonstrates antioxidant activity.
- Caffeoylquinic acid
- Exhibits inhibitory activities with 33-62% reduction of melanin content at 100 μM concentration on a-MSH-stimulated B16 melanoma cells
- Potent melanogenesis inhibitor
- Inhibits expression of MITF, tyrosinase, TRP-1, and TRP-2
- Shows antioxidant activity