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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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hsa-miR-141-3p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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β-Ionone is a small organic compound (C13H20O, MW 192.30 g/mol) used in research as an apoptosis inducer with reported anti-cancer activity in gastric adenocarcinoma SGC7901 cells. It is supplied as solid and solution formats for in vitro and in vivo studies and includes solubility and storage recommendations for reliable handling.
High purity (≈99.85%).
Available as solid and DMSO solution formats for experimental use.
Soluble in DMSO and ethanol; insoluble in water.
Storage recommendations for pure form and for solutions to preserve stability.
Acts as an apoptosis inducer in cell studies.
Molecular formula C13H20O; molecular weight 192.30 g/mol.
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LIT-927 is a locally and orally active CXCL12 neutraligand with an anti-inflammatory effect, exhibiting a Ki of 267 nM for CXCL12 binding to its specific receptor CXCR4.
Locally active
Orally active
CXCL12 neutraligand
Anti-inflammatory effect
Exhibits a Ki of 267 nM for CXCL12 binding to its specific receptor CXCR4
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SP-141 is a specific inhibitor of MDM2. It promotes MDM2 auto-ubiquitination and degradation. This compound may be used for the research of pancreatic cancer and breast cancer cells.
Specific inhibitor of MDM2.
Promotes MDM2 auto-ubiquitination and degradation.
Potential for research in pancreatic cancer and breast cancer cells.
Inhibits human pancreatic cancer cell growth with IC50 values of less than 0.5 μM in a p53-independent manner.
Shows selective cytotoxicity for cancer cells.
Induces MDM2 auto-ubiquitination and proteasomal degradation.
Suppresses pancreatic tumor growth in both xenograft and orthotopic mouse models.
Reduced tumor volume by 75% in a pancreatic xenograft model without significant differences in body weight in one study.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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