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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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BAY 80-6946 (Copanlisib CAS number 1032568-63-0) is a small molecule inhibitor targeting class I phosphatidylinositol-3-kinase (PI3K) with potent inhibitory activity against PI3K- and PI3K- isoforms By blocking PI3K enzymatic activity Copanlisib interferes with downstream signaling pathways crucial for cell proliferation and survival In vitro studies demonstrate notable antiproliferative effects in cancer cell lines such as HuCCT-1 and EGI-1 (KRASG12D mutants) exhibiting IC50 values of approximately 147 nM and 137 nM respectively Clinical trials indicate potential utility in treating B-cell malignancies like chronic lymphocytic leukemia and non-Hodgkin lymphoma
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1 3-Dihydroxyacetone (DHA) the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans 1 3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2]
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
1 3-Dihydroxyacetone (DHA) the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans 1 3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227)[1][2]
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More