Carbonyl compounds
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Medchemexpress LLC Niclosamide-13C6 | 1325808-64-7 | 99.0% | 5 MG
Niclosamide-13C6 is the 13C6 labeled Niclosamide, an orally bioavailable chlorinated salicylanilide. It exhibits anthelmintic and potential antineoplastic activity, inhibiting STAT3 with an IC50 of 0.25 μM in HeLa cells and DNA replication in a cell-free assay. Stable heavy isotopes of carbon have been incorporated into this molecule, primarily for quantitation during drug development.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
