Aminobenzoic acids and derivatives
eMolecules 106037-36-9 | 4-amino-3-methylbenzamide | MFCD08061918 | 5g
Ambeed | 1-(4-Methoxybenzyl)-4-(4455-tetramethyl-132-dioxaborolan-2-yl)-1H-pyrazole | 1g | 572945307 | A340561 | 1105039-88-0 | MFCD16877287 | 314.190 | C17H23BN2O3
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Chemscene ChemScene | 2-Amino-N-methylbenzamide | 25G | CS-W004940 | 0.98 | 818728| MFCD00060602 | 150.18
ChemScene | 2-Amino-N-methylbenzamide | 25G | CS-W004940 | 0.98 | 818728| MFCD00060602 | 150.18
Selleck Chemical LLC 3-Aminobenzamide S1132-25mg
3-Aminobenzamide (3-ABA 3-Amino Benzamide 3-AB) is a potent inhibitor of Poly(ADP-ribose)polymerase (PARP) and inhibits cell apoptosis after SCI (Spinal Cord Injury) in caspase-independent way
Medchemexpress LLC 4-methylbenzamide oxime | 19227-13-5 | MFCD00019952 | 99.2% | 150.18 g/mol | C8H10N2O | 25 G
4-Methylbenzamide oxime (CAS 19227-13-5) is a white to off-white solid used as a model benzamide oxime and as a substrate for mitochondrial amidoxime reducing component (mARC) enzyme reduction in biochemical assays. It is supplied at high purity and should be stored cold according to handling instructions in the SDS.
- Model substrate for mARC enzyme assays
- High purity (99.17%)
- Molecular formula C8H10N2O; molecular weight 150.18 g/mol
- White to off-white solid
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years)
Accela Chembio Inc 4-amino-n-methylbenzamide | 25g | 6274-22-2 | MFCD00665792 | 97+% | Shelf Life: 2160 Days | Light Sensitive
4-amino-n-methylbenzamide | 25g | 6274-22-2 | MFCD00665792 | 97+% | Shelf Life: 2160 Days | Light Sensitive
eMolecules 3544-24-9 | 3-Aminobenzamide | Oakwood Chemicals | MFCD00007989 | 136.154 | C7H8N2O | 98.000 | NC(=O)c1cccc(N)c1 | 250mg | 486551513
3-Aminobenzamide | Oakwood Chemicals | 3544-24-9 | MFCD00007989 | 136.154 | C7H8N2O | 98.000 | NC(=O)c1cccc(N)c1 | 250mg | 486551513
eMolecules 4-Guanidinobenzoic acid methanesulfonate | 148720-07-4 | MFCD00191442 | 1g
Combi-Blocks | 4-Guanidinobenzoic acid methanesulfonate | 1g | 267197711 | QE-2673 | 95.000 | 148720-07-4 | MFCD00191442 | 275.280 | C9H13N3O5S
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Medchemexpress LLC Obatoclax Mesylate | 803712-79-0 | 99.9% | 413.49 | 25 MG
Obatoclax Mesylate, also known as GX15-070 Mesylate, is a BH3 mimetic that acts as a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2. It induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. This compound exhibits anti-cancer and broad-spectrum antiparasitic activities.
- It is a pan-BCL-2 family proteins inhibitor.
- It induces autophagy-dependent cell death.
- It targets cyclin D1 for proteasomal degradation.
- It possesses anti-cancer activity.
- It demonstrates broad-spectrum antiparasitic activity.
Medchemexpress LLC Exatecan (mesylate) (GMP) | 169869-90-3 | 531.55 | 100 MG
Exatecan mesylate (DX8951f) GMP is a GMP-class Exatecan, a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
- DNA topoisomerase I inhibitor
- Potent antitumor activity against human tumors in vitro and in vivo
- Inhibits tumor growth in various cancer cell lines
- Prevents lung metastasis in orthotopic implantation mouse models
Selleck Chemical LLC KB-R7943 mesylate S4643-5mg
KB-R7943 mesylate is a widely used inhibitor of the reverse Na /Ca2 exchanger (NCX(rev)) with IC50 of 5 7 M KB-R7943 mesylate promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux
Apexbio Technology LLC Saquinavir mesylate 149845-06-7 10mM (in 1mL DMSO)
Saquinavir mesylate is a reversible inhibitor of HIV protease a retroviral aspartic protease required for viral maturation and replication It targets the active site of HIV-1 and HIV-2 proteases preventing enzymatic cleavage of polyprotein precursors thereby suppressing formation of mature viral particles Saquinavir inhibits HIV-1 protease with a reported Ki value of approximately 0 12 nM In cultured human neuronal cells it also reduces -amyloid (A 40) levels and inhibits -secretase (BACE1) activity at 50 M concentration it reduces neuronal A production by approximately 90% Saquinavir is commonly employed in HIV/AIDS research and has potential in Alzheimer s disease models for studying the modulation of amyloid peptide synthesis pathways
Medchemexpress LLC Safinamide mesylate | 202825-46-5 | 99.1% | C18H23FN2O5S | 5 MG
Safinamide mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 nM). It also blocks sodium channels and modulates glutamate (Glu) release, showing greater affinity at depolarized (IC50=8 μM) than at resting (IC50=262 μM) potentials. It exhibits neuroprotective and neurorescuing effects and can be used for the study of Parkinson's disease, ischemic stroke, and other conditions.
- Potent, selective, and reversible monoamine oxidase B inhibitor
- Blocks sodium channels
- Modulates glutamate release
- Exhibits neuroprotective and neurorescuing effects
- Suitable for the study of Parkinson's disease and ischemic stroke
Medchemexpress LLC Pritelivir mesylate hydrate | 1428321-10-1 | C19H24N4O7S3 | 5 MG
Pritelivir mesylate hydrate, also known as BAY 57-1293 mesylate hydrate, functions as an inhibitor of the viral helicase-primase complex. It demonstrates antiviral activity both in vitro and in animal models against herpes simplex virus (HSV) infection.
- Effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with an IC50 of 0.02 μM.
- First in class of antiviral agents targeting the viral helicase-primase enzyme complex.
- Significantly increases survival in animal models at doses of 0.03-45 mg/kg.
- Reduces mortality against HSV-1, E-377 at doses of 0.3-30 mg/kg.
- Protective against HSV-2, strain MS, in combination with Acyclovir.
Medchemexpress LLC KB-R7943 mesylate | 182004-65-5 | C17H21N3O6S2 | 1 ML
KB-R7943 mesylate is an inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with an IC50 of 5.7 ± 2.1 μM. It induces cancer cell death by activating the JNK pathway and blocking autophagic flux.
- Blocks NMDAR-mediated ion currents.
- Inhibits NMDA-induced increase in cytosolic Ca2+ (IC50 = 13.4 ± 3.6 μM).
- Accelerates calcium deregulation and mitochondrial depolarization in glutamate-treated neurons.
- Depolarizes mitochondria in a Ca2+-independent manner.
- Inhibits 2,4-dinitrophenol-stimulated respiration (IC50 = 11.4 ± 2.4 μM).
- Dose-dependently and reversibly blocks ion currents elicited by NMDA.
- Inhibits ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels.
- Inhibits both IhERG and native IKr (IC50 values of ~89 nM and ~120 nM, respectively).