Aminobenzoic acids and derivatives
Medchemexpress LLC Apilimod mesylate | 870087-36-8 | 99.8% | 610.70 | 50 MG
Apilimod mesylate is a chemical compound known for its potent inhibitory action against IL-12 and IL-23, with strong suppression of IL-12 at nanomolar concentrations. Additionally, it functions as a highly selective PIKfyve inhibitor, making it valuable for relevant biological research.
- Potent IL-12/IL-23 inhibitor
- Strongly inhibits IL-12 at nanomolar concentrations
- Functions as a potent and highly selective PIKfyve inhibitor
- Appears as a white to off-white solid
- Inhibits IFN-γ production
- Reduces serum IL-12 p40 levels in vivo
Medchemexpress LLC Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate | 138489-18-6 | 99.6% | 553.65 | 100 MG
Ro 31-8220 mesylate is a potent PKC inhibitor that also significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β. It shows no effect on MKK3, MKK4, MKK6, and MKK7. This compound can inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, demonstrating pharmacological properties independent of PKC. It also directly suppresses voltage-dependent Na+ channels and exhibits neuroprotective qualities.
- Potent PKC inhibitor with low nanomolar IC50s for various PKC isoforms
- Significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β
- Can inhibit MKP-1 expression and activate JNK
- Directly suppresses voltage-dependent Na+ channels
- Neuroprotective against paraoxon-induced neuronal cell death
Medchemexpress LLC Pritelivir mesylate hydrate | 1428321-10-1 | C19H24N4O7S3 | 50 MG
Pritelivir mesylate hydrate | 1428321-10-1 | C19H24N4O7S3 | 50 MG
Medchemexpress LLC Purinostat mesylate | 2650188-32-0 | 99.5% | 586.62 g/mol | C24H30N10O6S | 10 MG
Purinostat mesylate is the mesylate salt of purinostat, a potent and selective histone deacetylase (HDAC) inhibitor used in preclinical research. It exhibits low-nanomolar potency against multiple HDAC isoforms and has demonstrated apoptosis induction and cell-cycle effects in cancer models. The product is supplied as a solid or as a ready-to-use DMSO solution for laboratory studies.
- Potent HDAC inhibition at low-nanomolar concentrations.
- Selective for class I and class IIb HDACs.
- Demonstrated anti-leukemia activity in preclinical models.
- Available as a solid and as a 10 mM solution in DMSO.
- High purity (approximately 99.5%).
- Includes supporting documentation: data sheet, COA, SDS, H-NMR, and LC-MS.
Medchemexpress LLC PF-04217903 mesylate | 956906-93-7 | 99.8% | 1 ML
PF-04217903 mesylate is the methanesulfonate salt of a potent ATP-competitive c-Met (HGFR) kinase inhibitor supplied as a high-purity research compound for biochemical and cell-based studies.
- Potent ATP-competitive c-Met kinase inhibitor (Ki = 4.8 nM).
- High purity, 99.82%.
- Molecular weight 468.49 and formula C20H20N8O4S.
- Available as 10 mM solution in DMSO, 1 mL, and as solids in multiple masses.
- Suitable for in vitro biochemical and cellular assays.
Medchemexpress LLC Pamufetinib mesylate | 1688673-09-7 | 99.2% | 614.66 g/mol | C28H27FN4O7S2 | 100MG
Pamufetinib mesylate is an ATP-competitive, small-molecule inhibitor that targets vascular endothelial growth factor receptor (VEGFR) and hepatocyte growth factor receptor (c-Met/HGFR). Supplied as the mesylate salt for research use only, it exhibits potent in vitro kinase inhibition and is provided as a high-purity solid with recommended storage conditions to preserve stability.
- Potent dual inhibition of VEGFR2 and MET (IC50 ≈ 30-32 nM).
- High reported purity (99.2%).
- Provided as a mesylate salt to improve handling and solubility for assays.
- Available in a 100 mg pack size for research applications.
- Solid, white to off-white appearance suitable for accurate weighing.
- Storage recommendations: 4°C for powder; in solvent -80°C for long-term stability.
Medchemexpress LLC Purinostat mesylate | 2650188-32-0 | 99.5% | 586.62 | 5 MG
Purinostat mesylate is a selective inhibitor of HDAC, inhibiting class I and class IIb HDACs with IC50s ranging from 0.81 to 11.5 nM. It induces apoptosis and affects the cell cycle, demonstrating potent anti-leukemia effects in vivo. This product can be used for research on lymphoblastic leukemia.
- Selective inhibitor of HDAC
- Inhibits class I and class IIb HDACs
- Induces apoptosis
- Affects the cell cycle of LAMA84 and 188 BL-2 cells
- Demonstrates potent anti-leukemia effects in vivo
- Can be used for research on lymphoblastic leukemia
Medchemexpress LLC Masitinib mesylate | 1048007-93-7 | MFCD12546334 | 100.0% | 594.75 g/mol | C29H34N6O4S2 | 25 MG
Masitinib mesylate is a research-grade small-molecule tyrosine kinase inhibitor primarily targeting c-Kit and used in preclinical studies to assess antiproliferative and pro-apoptotic effects. It is supplied as a high-purity solid with documented solubility and storage recommendations for research use.
- Potent inhibitor of c-Kit with reported IC50 ≈ 200 nM.
- High reported purity suitable for analytical and biological studies.
- Supplied as a white to yellow solid with characterized physical properties.
- Documented solubility in DMSO and acidic aqueous media for formulation.
- Storage recommendations provided to preserve stability in solvent and solid form.
Medchemexpress LLC Larotinib mesylate hydrate | 2097129-93-4 | C26H36ClFN4O11S2 | 100 MG
Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC50 of 0.6 nM. This compound is intended for research use only.
- Inhibits EGFRL861Q (IC50: 0.423 nM)
- Inhibits EGFRL858R (IC50: 0.563 nM)
- Inhibits EGFR (WT) (IC50: 0.611 nM)
- Inhibits EGFRT790M (IC50: 45.2 nM)
- Inhibits HER4 (IC50: 84 nM)
- Inhibits BLK (IC50: 102 nM)
- Inhibits IRAK-1 (IC50: 167 nM)
- Inhibits BTK (IC50: 196 nM)
- Inhibits HER2 (IC50: 253 nM)
Medchemexpress LLC DOTAP mesylate 25mg
DOTAP mesylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Camostat mesylate | 59721-29-8 | MFCD00941410 | 100.0% | C21H26N4O8S | 10MG
Camostat mesylate is an orally active synthetic serine protease inhibitor used in biochemical and antiviral research. It inhibits trypsin-like proteases including TMPRSS2 and is applied in studies of protease function, viral entry inhibition, and inflammatory pathways. Supplied as a high-purity standard for laboratory assays and pharmacological research.
- Targets TMPRSS2 and trypsin-like serine proteases.
- High purity suitable for analytical and biological assays (reported 99.96%).
- Molecular formula C21H26N4O8S and molecular weight 494.52.
- Supplied as a solid reference material for in vitro and biochemical studies.
- Relevant for antiviral research, protease inhibition assays, and inflammation studies.
Medchemexpress LLC Cp-506 mesylate | 2227304-19-8 | 98.6% | 681.60 | 5 MG
Cp-506 mesylate is a light yellow to yellow solid. This product has been tested and complies with the given specifications. It is important to note that this product has not been fully validated for medical applications and is intended for research use only.
- Cas number: 2227304-19-8
- Molecular weight: 681.60
- Purity: 98.59%
- Storage conditions for powder: -20°C for 3 years, 4°C for 2 years
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Reboxetine mesylate | 98769-84-7 | MFCD02184016 | 99.7% | 409.50 g·mol⁻1 | C20H27NO6S | 5 MG
Reboxetine mesylate is the methanesulfonate salt of reboxetine, a selective noradrenaline reuptake inhibitor used as a research compound to study norepinephrine transporter function and neuropharmacology. It is supplied as a high-purity research chemical for in vitro and in vivo experimental applications; CAS 98769-84-7, molecular weight 409.50 g·mol⁻1.
- Selective noradrenaline reuptake inhibitor activity for transporter studies.
- Suitable for in vitro and in vivo research applications.
- High purity suitable for analytical and pharmacological assays.
- Available in small milligram quantities for laboratory use.
- Provided with referenced product documentation and datasheet.
Selleck Chemical LLC Nafamostat mesilate (FUT-175) S1386-1g
Nafamostat mesilate is a synthetic serine protease inhibitor used as an anticoagulant during hemodialysis Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19 Nafamostat Mesilate attenuates inflammation and apoptosis
eMolecules 138-14-7 | Deferoxamine Mesylate | Ambeed | MFCD00058605 | 656.790 | C26H52N6O11S | 98.000 | CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN | 250mg | 596330728
Deferoxamine Mesylate | Ambeed | 138-14-7 | MFCD00058605 | 656.790 | C26H52N6O11S | 98.000 | CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN | 250mg | 596330728