Anilides
Medchemexpress LLC Animal-free NAP-2/CXCL7 protein, human (His) | >95.0% | 2UG
Recombinant human NAP-2/CXCL7 protein fragment with an N-terminal 6xHis tag, produced in E. coli and supplied with a certificate of analysis. The preparation corresponds to residues A59-D128 (70 amino acids), has an approximate molecular weight of ~11 kDa, and is ≥95.0% pure by reducing SDS-PAGE. For research use only.
- Recombinant fragment representing residues A59-D128.
- N-terminal 6xHis tag for purification and detection.
- Produced in E. coli for efficient expression.
- Purity ≥95.0% as determined by reducing SDS-PAGE.
- Provided with a certificate of analysis for batch-specific data.
- Suitable for biochemical assays and antibody development.
Apexbio Technology LLC S-Nitroso-N-acetyl-DL-penicillamine 67776-06-1 25mg
S-Nitroso-N-acetyl-DL-penicillamine (SNAP CAS 67776-06-1) is a low-molecular-weight nitric oxide (NO) donor that facilitates the sustained release of NO in biological systems By elevating NO levels SNAP stimulates soluble guanylate cyclase activity resulting in increased cyclic guanosine monophosphate (cGMP) production and subsequent modulation of downstream signaling pathways These actions contribute to vascular smooth muscle relaxation and vasodilation SNAP is widely employed in experimental studies to investigate NO-mediated mechanisms including inhibition of platelet aggregation and regulation of inflammatory responses and serves as a valuable reagent for probing NO signaling in cultured cells
![Medchemexpress LLC N-[2-methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]... | 1211866-85-1 | MFCD22123242 | 99.7% | 516.52 g/mol | C25H27F3N6O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239841.png-250.jpg)
Medchemexpress LLC N-[2-methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]piperidin-1-yl]-1,3,5-triazin-2-yl]amino]phenyl]... | 1211866-85-1 | MFCD22123242 | 99.7% | 516.52 g/mol | C25H27F3N6O3 | 5 MG
Potent, orally active Nav1.7 sodium channel inhibitor intended for research use in ion-channel pharmacology and analgesia studies. The compound is a well-characterized small molecule with high reported purity and documented activity across human and rodent NaV subtypes; supplied in solid and solution formats with recommended cold storage.
Medchemexpress LLC Leflunomide | 75706-12-6 | C12H9F3N2O2 | 500 MG
Leflunomide is a pyrimidine synthesis inhibitor, primarily functioning by inhibiting dihydroorotate dehydrogenase (DHODH), and is recognized as a disease-modifying antirheumatic agent. This prodrug inhibits the proliferation of mononuclear and T-cells and acts as an inhibitor of several protein tyrosine kinases, with IC50 values ranging from 30 mM to 100 mM in in vitro assays. It also interferes with cell cycle progression and utilizes p53-dependent mechanisms to prevent the expansion of activated and autoimmune lymphocytes.
- Inhibits dihydroorotate dehydrogenase (DHODH)
- Acts as a disease-modifying antirheumatic agent
- Inhibits proliferation of mononuclear and T-cells
- Functions as an inhibitor of several protein tyrosine kinases
- Inhibits p59fyn and p56lck activity in tyrosine kinase assays
- Inhibits calcium mobilization in Jurkat cells
- Prevents expansion of activated and autoimmune lymphocytes
Cambridge Isotope Laboratories Resveratrol (4-hydroxyphenyl-13C6 99%) 1 mg
Resveratrol (4-hydroxyphenyl-13C6 99%) 1 mg
![Medchemexpress LLC 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-3-pyridinecarboxamide | 188425-85-6 | 99.8% | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000233956.png-250.jpg)
Medchemexpress LLC 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-3-pyridinecarboxamide | 188425-85-6 | 99.8% | 500 MG
Boscalid is a broad-spectrum carboxamide fungicide and succinate dehydrogenase (SDH) inhibitor supplied as a solid analytical standard for research and analytical applications. Typical pack contains 500 MG with a listed purity of 99.8%.
- High purity of 99.8% suitable for analytical use.
- Formula C18H12Cl2N2O with molecular weight 343.21 g·mol⁻¹.
- Solid powder appearance for easy handling and formulation.
- Storage: powder stable at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent store at -80°C (6 months) or -20°C (1 month).
- Mode of action: succinate dehydrogenase (SDH) inhibitor useful in fungal respiration studies.
- Intended for research and analytical applications; not for human or veterinary use.
Medchemexpress LLC (S)-1,1'-bi-2,2'-naphthol | 18531-99-2 | MFCD00004068 | 100.0% | 286.32 | C20H14O2 | 25 G
(S)-1,1'-Bi-2,2'-naphthol (S)-BINOL is a chiral diol used widely as a ligand and chiral auxiliary in asymmetric synthesis and catalysis. It is supplied as a white to off-white solid with high purity, intended for research use in organic synthesis, catalyst development, and related life-science applications.
- Chiral ligand for asymmetric catalysis and ligand design.
- High purity suitable for research and synthesis.
- Solid, white to off-white appearance for easy handling.
- Stable under recommended storage conditions for prolonged shelf life.
- Useful as a starting material or chiral auxiliary in academic and industrial research.
Apexbio Technology LLC Leflunomide 75706-12-6 10mM (in 1mL DMSO)
Leflunomide (CAS 75706-12-6) is a small-molecule agonist targeting the aryl hydrocarbon receptor (AHR) pathway It is designed to modulate AHR signaling thereby enhancing regulatory T cell (Treg) numbers altering inflammatory cytokine profiles and influencing immune responses Leflunomide exerts its biological activity primarily through metabolic conversion to its active metabolite Teriflunomide (A771726) which mediates immunosuppressive effects It enhances IL-10 production and suppresses IL-17 and IL-23 secretion In cell-based studies leflunomide demonstrates anti-proliferative efficacy in human medullary thyroid carcinoma cells (MTC-TT) with IC50 values ranging from approximately 30 to 50 M depending on specific assay conditions Based on these pharmacological properties leflunomide holds research potential in ischemia-reperfusion renal injury sepsis-induced intestinal oxidative stress and tumor proliferation inhibition models
Medchemexpress LLC NAP-2/CXCL7 Rat CH 2ug
CXCL7 (also known as neutrophil activating peptide 2 NAP-2) is a platelet-derived growth factor that belongs to the ELR CXC chemokine family functioning as a potent chemoattractant and activator of neutrophils through binding to its receptor CXCR2[1] NAP-2/CXCL7 Protein Rat (CHO) is produced in CHO cells and consists of 62 amino acids (I46-I107)
Medchemexpress LLC (S)-1,1'-bi-2,2'-naphthol | 18531-99-2 | MFCD00004068 | 100.0% | 286.32 | C20H14O2 | 1 ML
(S)-1,1'-Bi-2,2'-naphthol is a chiral diol used as a ligand and chiral auxiliary in asymmetric synthesis and catalysis. Supplied as a 10 mM solution in DMSO for research use, it facilitates formation of chiral catalysts, supports enantioselective transformations, and aids method development in organic synthesis.
- Chiral diol useful as a ligand for asymmetric catalysis.
- High chemical purity suitable for research and analytical applications.
- Provided as a 10 mM solution ready for reconstitution or direct use.
- Characterized by supporting analytical data such as COA, 1H NMR, and RP-HPLC.
Medchemexpress LLC Boscalid | 188425-85-6 | 99.8% | 1 G
Boscalid is a fungicidal research chemical that inhibits succinate dehydrogenase (SDH), disrupting fungal respiration. It is supplied for research and analytical applications and is available as a solid or as a 10 mM solution in DMSO.
- Provides fungicidal activity as a succinate dehydrogenase inhibitor
- High purity suitable for analytical use (99.8%)
- Molecular formula C18H12Cl2N2O; molecular weight 343.21 g/mol
- Available in solid form and as a 10 mM solution in DMSO; common pack sizes include 50 mg-1 g
- Intended for research use only; not for human or veterinary use
Apexbio Technology LLC S-Nitroso-N-acetyl-DL-penicillamine 67776-06-1 50mg
S-Nitroso-N-acetyl-DL-penicillamine (SNAP CAS 67776-06-1) is a low-molecular-weight nitric oxide (NO) donor that facilitates the sustained release of NO in biological systems By elevating NO levels SNAP stimulates soluble guanylate cyclase activity resulting in increased cyclic guanosine monophosphate (cGMP) production and subsequent modulation of downstream signaling pathways These actions contribute to vascular smooth muscle relaxation and vasodilation SNAP is widely employed in experimental studies to investigate NO-mediated mechanisms including inhibition of platelet aggregation and regulation of inflammatory responses and serves as a valuable reagent for probing NO signaling in cultured cells