Benzenesulfonamides
Apexbio Technology LLC WAY 316606 5MG
WAY 316606 (CAS 915759-45-4) is a selective small molecule inhibitor targeting secreted frizzled-related protein 1 (sFRP-1) an endogenous antagonist of Wnt signaling WAY 316606 binds specifically to sFRP-1 (Kd 0 08 M) reducing its inhibitory effect and thus activating the canonical Wnt pathway In cell-based reporter assays using U2-OS osteosarcoma cells WAY 316606 dose-dependently promoted Wnt signaling with an EC50 of 0 65 M Ex vivo studies with neonatal murine calvarial tissue further demonstrated that WAY 316606 enhances osteoblast activity and bone formation This compound serves as a research tool for investigating Wnt-associated bone metabolism and therapeutic strategies for metabolic bone disorders
eMolecules Sulfachloropyridazine sodium | 23282-55-5 | | 5g
Combi-Blocks | Sulfachloropyridazine sodium | 5g | 205403345 | QA-6187 | 98.000 | 23282-55-5 | | 306.700 | C10H8ClN4NaO2S
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![eMolecules 4-Chloro-1-(phenylsulfonyl)-5-(trifluoromethyl)-1h-pyrrolo[2,3-b]pyridine-2-carboxylic acid | 1299607-39-8 | MFCD18803508 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502192383.JPG-250.jpg)
eMolecules 4-Chloro-1-(phenylsulfonyl)-5-(trifluoromethyl)-1h-pyrrolo[2,3-b]pyridine-2-carboxylic acid | 1299607-39-8 | MFCD18803508 | 1g
Combi-Blocks | 4-Chloro-1-(phenylsulfonyl)-5-(trifluoromethyl)-1h-pyrrolo[2,3-b]pyridine-2-carboxylic acid | 1g | 401043950 | QB-9131 | 95.000 | 1299607-39-8 | MFCD18803508 | 404.740 | C15H8ClF3N2O4S
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eMolecules 3-(Acetyloxy)-4-nitrophenylboronic acid | 2096337-62-9 | MFCD19684104 | 1g
Combi-Blocks | 3-(Acetyloxy)-4-nitrophenylboronic acid | 1g | 117523381 | BB-4050 | 95.000 | 2096337-62-9 | MFCD19684104 | 224.960 | C8H8BNO6
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AdipoGen Glimepiride (1 g)
Chemical. CAS: 93479-97-1. Formula: C24H34N4O5S. MW: 490.62. Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase and stimulates glucose transporter 1 and 4 (GLUT1/4) expression. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway and exhibits neuroprotective benefit, decreasing expression and activity of BACE1 and amyloid-beta (Abeta) in neurons in a PPARgamma-dependent manner.
Medchemexpress LLC HY-100506 1mg Medchemexpress, GLPG0187 CAS:1320346-97-1 Purity:>98%
Medchemexpress, HY-100506 1mg GLPG0187 CAS:1320346-97-1 GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103000 10mg Medchemexpress, HSF1A CAS:1196723-93-9 Purity:>98%
Medchemexpress, HY-103000 10mg HSF1A CAS:1196723-93-9 HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-A0013A 500mg Medchemexpress, Bosentan (hydrate) CAS:157212-55-0 Purity:>98%
Medchemexpress, HY-A0013A 500mg Bosentan (hydrate) CAS:157212-55-0 Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-A0013 500mg Medchemexpress, Bosentan CAS:147536-97-8 Purity:>98%
Medchemexpress, HY-A0013 500mg Bosentan CAS:147536-97-8 Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 2-HYDROXYETHYL BENZENESULFONATE | 249285-50-5 | MFCD23160722 | 500mg
WuXi ChemSupply | 2-HYDROXYETHYL BENZENESULFONATE | 500mg | 599167414 | LN01277743 | 95.000 | 249285-50-5 | MFCD23160722 | 202.220 | C8H10O4S
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![eMolecules 1-(benzenesulfonyl)-3-bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine | 1638761-42-8 | MFCD27987368 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502157883.JPG-250.jpg)
eMolecules 1-(benzenesulfonyl)-3-bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine | 1638761-42-8 | MFCD27987368 | 1g
Pharmablock | 1-(benzenesulfonyl)-3-bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine | 1g | 551113561 | PBLJ1019 | | 1638761-42-8 | MFCD27987368 | 371.630 | C13H8BrClN2O2S
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![eMolecules 1-(benzenesulfonyl)-5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine | 876343-81-6 | MFCD11616450 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502157927.JPG-250.jpg)
eMolecules 1-(benzenesulfonyl)-5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine | 876343-81-6 | MFCD11616450 | 1g
Pharmablock | 1-(benzenesulfonyl)-5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine | 1g | 551203600 | PB03808 | | 876343-81-6 | MFCD11616450 | 371.630 | C13H8BrClN2O2S
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eMolecules 4-(Piperidin-1-ylsulfonyl)phenylboronic acid | 486422-58-6 | MFCD06659850 | 1g
Combi-Blocks | 4-(Piperidin-1-ylsulfonyl)phenylboronic acid | 1g | 117521176 | BB-2425 | 98.000 | 486422-58-6 | MFCD06659850 | 269.120 | C11H16BNO4S
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eMolecules 3-N-Morpholinylsulfonylphenylboronic acid | 871329-60-1 | MFCD07363748 | 1g
Combi-Blocks | 3-N-Morpholinylsulfonylphenylboronic acid | 1g | 117521027 | BB-2351 | 98.000 | 871329-60-1 | MFCD07363748 | 271.090 | C10H14BNO5S
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![eMolecules 2-[(4-Hydroxy-3-nitrobenzene)sulfonamido]benzoic acid | 131971-24-9 | MFCD02708220 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502187076.JPG-250.jpg)
eMolecules 2-[(4-Hydroxy-3-nitrobenzene)sulfonamido]benzoic acid | 131971-24-9 | MFCD02708220 | 1g
Combi-Blocks | 2-[(4-Hydroxy-3-nitrobenzene)sulfonamido]benzoic acid | 1g | 296391304 | OT-4146 | 95.000 | 131971-24-9 | MFCD02708220 | 338.290 | C13H10N2O7S
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