Benzenesulfonamides
Electron Microscopy Sciences SEM Scintillator YAP 12.0x17 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with Zeiss SEM scanning electron microscopes.
Sigma Aldrich Fine Chemicals Biosciences Ribonucleic acid from torula yeast Type VI | 63231-63-0 | MFCD00132195 | 25g
Ribonucleic acid from torula yeast Type VI | 63231-63-0 | MFCD00132195 | 25g
Medchemexpress LLC Sulfacetamide sodium | 127-56-0 | 99.7% | 25 G
Sulfacetamide sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. It exhibits antifungal and antibacterial activities.
- Used for the study of various ocular infections like trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea
- Acts as an antifungal agent through a CYP51A1-independent mechanism
- Bacteriostatic agent with similar activity against both Gram-positive and Gram-negative bacteria
Medchemexpress LLC HY-111941 10mg Medchemexpress, GSK8612 CAS:2361659-62-1 Purity:>98%
Medchemexpress, HY-111941 10mg GSK8612 CAS:2361659-62-1 GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC IACS-13909 | 2160546-07-4 | 99.97% | 377.27 | 25 MG
IACS-13909 is a selective, potent, and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. It demonstrates greater selectivity for SHP2 compared to other phosphatases, including SHP1. This compound exhibits antitumor activities and effectively suppresses MAPK pathway signaling in receptor tyrosine kinase (RTK)-dependent cancers.
- Selective, potent, and orally active SHP2 allosteric inhibitor
- Greater selectivity for SHP2 compared to other phosphatases
- Exhibits antitumor activities
- Suppresses MAPK pathway signaling in RTK-dependent cancers
Medchemexpress LLC HY-A0013A 500mg Medchemexpress, Bosentan (hydrate) CAS:157212-55-0 Purity:>98%
Medchemexpress, HY-A0013A 500mg Bosentan (hydrate) CAS:157212-55-0 Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Glimepiride | 93479-97-1 | 99.9% | C24H34N4O5S | 5 G
Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound. It has shown to lower blood glucose more effectively than glibenclamide and may decrease extracellular Aβ40 and Aβ42 levels, suggesting its potential for Alzheimer's disease associated with diabetes.
- Medium-to-long acting sulfonylurea anti-diabetic compound.
- Lower risk of hypoglycemia and less weight gain compared to other sulfonylureas.
- May be safer for patients with cardiovascular disease due to a lack of detrimental effects on ischemic preconditioning.
- Potential for Alzheimer's disease associated with diabetes by decreasing extracellular Aβ40 and Aβ42 levels.
Sigma Aldrich Fine Chemicals Biosciences Glimepiride for system suitability European Pharmacopoeia (EP) Reference Standard | 93479-97-1 | MFCD00878417 |
Glimepiride for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 490.62 | 93479-97-1 | MFCD00878417 |
Medchemexpress LLC Orexin receptor antagonist 2 | 1457940-75-8 | 98.1% | 433.55 | 50 MG
Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. It has the potential for the research of insomnia and is for research use only.
- Potent orexin receptor antagonist
- Potential for insomnia research
- For research use only
eMolecules 1005264-47-0 | Medchem Express | MX69 | 5mg | 446256267 | HY-100892 | MFCD24858136 | 474.58 | C27H26N2O4S
Medchem Express | 14-Chrysenequinone | 50mg | 437899125 | HY-111441 | 100900-16-1 | MFCD00009941 | 258.276 | C18H10O2
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Medchemexpress LLC N-Benzyl-N-Cbz-glycine | 76315-01-0 | 265.31 | 1 G
N-Benzyl-N-Cbz-glycine is a derivative of Glycine, appearing as a white to off-white solid. This amino acid derivative is used as an ergogenic supplement, known to influence anabolic hormone secretion, provide fuel during exercise, enhance mental performance during stress, and help prevent exercise-induced muscle damage. It is recognized as a beneficial dietary substance for research use only.
- Derivative of glycine
- Used as an ergogenic supplement
- Influences anabolic hormone secretion
- Supplies fuel during exercise
- Improves mental performance during stress-related tasks
- Prevents exercise-induced muscle damage
- White to off-white solid appearance
- For research use only
Medchemexpress LLC Glimepiride | 93479-97-1 | 99.9% | C24H34N4O5S | 10 MM * 1 ML
Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. It is for research use only. It has been shown to decrease extracellular Aβ40 and Aβ42 levels, potentially serving as a promising drug for the treatment of AD associated with diabetes. Compared to other sulfonylureas, it is generally associated with a lower risk of hypoglycemia and less weight gain, and may be safer for patients with cardiovascular disease due to its lack of detrimental effects on ischemic preconditioning.
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Lowers blood glucose in rabbits more effectively than glibenclamide
- Associated with lower risk of hypoglycemia and less weight gain
- May be safer for patients with cardiovascular disease
Selleck Chemical LLC Succinylsulfathiazole S4585-100mg
Succinylsulfathiazole (Succinylsulphathiazole) a sulfonamide is an antibiotic
Medchemexpress LLC HMN-176 | 173529-10-7 | MFCD00945108 | 99.4% | 382.43 | 100 MG
HMN-176 is a stilbene derivative that inhibits mitosis by interfering with polo-like kinase-1 (PLK1), without significantly affecting tubulin polymerization. It is intended for research use only and is not sold to patients.
- Inhibits mitosis by interfering with polo-like kinase-1 (PLK1).
- Does not significantly affect tubulin polymerization.
- Increases mitosis duration in hTERT-RPE1 and CFPAC-1 cell lines (at 2.5 μM).
- Inhibits aster formation in a concentration-dependent manner.
- Demonstrates inhibitory effects in multiple tumors (breast, non-small-cell lung, ovarian).
- Shows potent cytotoxicity (mean IC50 of 118 nM).
- Suppresses MDR1 mRNA expression by 56% (at 3 μM).
Medchemexpress LLC Furosemide-d5 | 1189482-35-6 | 99.9% | 1 MG
Furosemide-d5 is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2. It also acts as a GABAA receptors antagonist, showing 100-fold selectivity for α6-containing receptors over α1-containing receptors. Furosemide is a loop diuretic used in the study of congestive heart failure, hypertension, and edema. Deuterium substitution in drug molecules is explored for its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter
- Acts as a GABAA receptors antagonist
- Used in the study of congestive heart failure, hypertension, and edema