Benzenesulfonamides
Medchemexpress LLC Sulfacetamide (standard) | 144-80-9 | 100 MG
Sulfacetamide (standard) | 144-80-9 | 100 MG
Medchemexpress LLC LPA2 antagonist 2 | 36840-10-5 | 95.0% | 380.35 | 10 MG
LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. It demonstrates high selectivity, being >480-fold more selective than LPA3 (IC50 of 13.85 μM), and inhibits LPA1 with an Imax of 59.0% at 30 μM. This chemical is intended for research use only.
- Selective antagonist for LPA2.
- Inhibits LPA1.
- Targets LPL receptor.
- Involved in the GPCR/G protein pathway.
- Suitable for in vitro research.
- Store at -20°C for powder and -80°C for solvent.
Selleck Chemical LLC MF-438
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with IC50 of 2 3 nM for rSCD1
Medchemexpress LLC N-desmethyl sildenafil | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 g/mol | C21H28N6O4S | 100 MG
N-desmethyl sildenafil is the primary human metabolite of sildenafil and is supplied as a high-purity reference standard for research use in studies of phosphodiesterase type 5 (PDE5) metabolism and pharmacology. It is intended for analytical, metabolic, and assay development applications.
- High purity suitable for analytical reference (reported 99.5%).
- Used as a metabolite reference in pharmacokinetic and metabolic pathway studies.
- Stable solid form for storage and handling in laboratory settings.
- Compatible with LC-MS and related analytical methods.
- Provided as a 100 MG sample for benchtop experiments and assay calibration.
Medchemexpress LLC Sulfacetamide (Standard) | 144-80-9 | 250 MG
Sulfacetamide (Standard) | 144-80-9 | 250 MG
Medchemexpress LLC YAP/TAZ inhibitor-2 | 2762617-31-0 | 99.8% | 390.33 | 50 MG
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. It demonstrates significant anti-proliferative and anti-tumor activity.
- Potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM.
- Shows antiproliferative activity with an IC50 value of 5.33 nM in NCI-H226 cells.
- Exhibits anti-tumor activity in BALB/c nude mice (NCI-H226 xenograft model) without significant body weight loss.
Selleck Chemical LLC CA3
CA3 (CIL56) has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties CA3(CIL56) induces ferroptosis and iron-dependent reactive oxygen species (ROS)
Medchemexpress LLC YAP/TAZ inhibitor-2 | 2762617-31-0 | 99.8% | 390.33 | 5 MG
YAP/TAZ inhibitor-2 is a potent and orally active TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM. It demonstrates significant anti-proliferative and anti-tumor activities in both in vitro and in vivo studies.
- Potent and orally active TEAD-YAP/TAZ inhibitor
- Displays anti-proliferative activity with an IC50 of 5.33 nM in NCI-H226 cells
- Demonstrates anti-tumor activity in BALB/c nude mice xenograft models
- EC50 value of 3 nM
Enzo Life Sciences NBQX . disodium salt (25mg). CAS: 118876-58-7 (non-salt)
Water soluble, potent and selective AMPA/kainate receptor antagonist. For literature references, see NBQX (ALX-550-044). Alternative name: 2,3-Dihydroxy-6-nitro-7-sulphamoylbenzo(f)-quinoxaline . 2Na, 6-Nitro-7-sulphamoylbenzo(f)-quinoxaline-2,3-dione . 2Na. Purity: ≥98% (HPLC). Solubility: Soluble in water (5mg/ml) or DMSO. Long Term Storage: -20°C.
Medchemexpress LLC MF-766 10mg | 1050656-06-8 | 478.46 | C27H21F3N2O3 | 10 MG
MF-766 is a potent, selective, and orally active antagonist of the prostaglandin E2 EP4 receptor, used as a research tool in inflammation, immunology, and oncology studies. It shows sub-nanomolar binding affinity and low-nanomolar functional inhibition in cell-based assays.
- Potent EP4 antagonist with Ki = 0.23 nM and IC50 ≈ 1.4 nM.
- Suitable for in vitro and in vivo studies; soluble in DMSO (50 mg/mL) and formulatable in 10% DMSO/90% corn oil.
- High chemical purity (≈99.8%) for consistent experimental results.
- Solid, white to off-white powder with recommended powder storage at -20°C for long-term stability.
- Available in small research sizes and as a 10 mM DMSO solution for convenience.
Selleck Chemical LLC Sildenafil-100mg
Sildenafil (Revatio, UK-92480, Viagra) is a Phosphodiesterase 5 Inhibitor with IC50 of 5.22 nM.
![eMolecules 171599-83-0 | SILDENAFIL CITRATE | AstaTech | MFCD09026931 | 666.700 | C28H38N6O11S | 95.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 25g | 410712234](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000162673.jpg-250.jpg)
eMolecules 171599-83-0 | SILDENAFIL CITRATE | AstaTech | MFCD09026931 | 666.700 | C28H38N6O11S | 95.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 25g | 410712234
SILDENAFIL CITRATE | AstaTech | 171599-83-0 | MFCD09026931 | 666.700 | C28H38N6O11S | 95.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 25g | 410712234
TARGETMOL CHEMICALS INC Sildenafil citrate 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertension. Purity 99.59%