Benzenesulfonamides
Medchemexpress LLC Methylenephosphonic acid CD73 inhibitor | 2216764-29-1 | 99.2% | 463.81 g·mol⁻¹ | C16H23ClN5O7P | 5 MG
CD73-IN-4 is a potent, selective methylenephosphonic acid inhibitor of ecto-5'-nucleotidase (CD73) with low-nanomolar activity against human CD73. It is supplied as a research reagent for biochemical and cell-based studies, with reported high purity and multiple pack size options. Molecular formula C16H23ClN5O7P; molecular weight 463.81 g·mol⁻¹.
Apexbio Technology LLC Benzenesulfonamide 98-10-2 500mg
Benzenesulfonamide (CAS 98-10-2) is an amide derivative of benzenesulfonic acid widely utilized as a synthetic intermediate for pharmaceuticals and other chemicals Mechanistically benzenesulfonamide derivatives have been investigated for their inhibitory activity against various human carbonic anhydrases (CAs) with certain 4-substituted diazo derivatives exhibiting strong binding affinity particularly for CA I and II isoforms as demonstrated by isothermal titration calorimetry and fluorescence-based thermal shift assays In in vivo models indole-based benzenesulfonamide derivatives show oral activity in rat and sheep models of airway inflammation attenuating physiological responses to antigenic or cholinergic challenge Benzenesulfonamide remains in preclinical evaluation
Apexbio Technology LLC Benzenesulfonamide 98-10-2 100mg
Benzenesulfonamide (CAS 98-10-2) is an amide derivative of benzenesulfonic acid widely utilized as a synthetic intermediate for pharmaceuticals and other chemicals Mechanistically benzenesulfonamide derivatives have been investigated for their inhibitory activity against various human carbonic anhydrases (CAs) with certain 4-substituted diazo derivatives exhibiting strong binding affinity particularly for CA I and II isoforms as demonstrated by isothermal titration calorimetry and fluorescence-based thermal shift assays In in vivo models indole-based benzenesulfonamide derivatives show oral activity in rat and sheep models of airway inflammation attenuating physiological responses to antigenic or cholinergic challenge Benzenesulfonamide remains in preclinical evaluation
Apexbio Technology LLC Sulfacetamide Sodium 127-56-0 5g
Sulfacetamide Sodium (127-56-0) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this enzyme thereby disrupting bacterial folic acid synthesis Sulfacetamide Sodium exerts its biological activity primarily through inhibition of bacterial dihydropteroate synthase In in vitro studies Sulfacetamide Sodium demonstrates bacteriostatic activity with inhibitory concentrations (IC50) ranging from 60 g/mL to 64 mg/mL dependent on the bacterial species studied Based on these pharmacological properties Sulfacetamide Sodium holds research potential in microbiological studies of antibacterial potency antibiotic susceptibility and resistance patterns
Apexbio Technology LLC Sulfaguanidine 57-67-0 50mg
Sulfaguanidine (57-67-0) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this enzyme thereby interfering with folic acid biosynthesis and disrupting a pathway critical for bacterial growth Sulfaguanidine exerts its biological activity primarily through competitive inhibition of bacterial dihydropteroate synthase In in vitro infection models sulfaguanidine demonstrates antimicrobial activity with reported IC50 values generally in the micromolar range depending on bacterial species experimental conditions and assay methodologies Based on these pharmacological properties sulfaguanidine holds research potential in studies of antimicrobial resistance mechanisms bacterial folate metabolism and interactions with other antimicrobial agents