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Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is a common dichloromethane solvate of the palladium catalyst Pd(dppf)Cl2. This phosphine ligand palladium(II) complex serves as a versatile precatalyst for various cross-coupling reactions. It efficiently catalyzes various cross-coupling reactions and is suitable for modifying complex bioactive molecules containing free amino groups, eliminating the need to change catalysts for different reaction types.
Stabilizes reaction intermediates
Lowers reaction activation energy in coupling reactions
Used in Suzuki-Miyaura coupling reaction studies
Product can be purified by column chromatography before biological activity testing
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