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Filtered Search Results
Medchemexpress LLC HY-112306 10mg Medchemexpress, Ripretinib CAS:1442472-39-0 Purity:>98%
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Medchemexpress, HY-112306 10mg Ripretinib CAS:1442472-39-0 Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2)[2]. DCC-2618 exerts antineoplastic effect and induces apoptosis[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem 1 2 3-Tribromobenzene | ≥97% | CAS 608-21-9 | C6H3Br3 | 5g
1 2 3-Tribromobenzene | ≥97% | CAS 608-21-9 | C6H3Br3 | 5g
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=O | 0.25g | 718057990](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502482493.JPG-250.jpg)
eMolecules 2493-04-1 | (5-NITROFURAN-2-YL)METHANOL | AstaTech | MFCD00272267 | 143.098 | C5H5NO4 | 95.000 | OCc1ccc(o1)[N+]([O-])=O | 0.25g | 718057990
(5-NITROFURAN-2-YL)METHANOL | AstaTech | 2493-04-1 | MFCD00272267 | 143.098 | C5H5NO4 | 95.000 | OCc1ccc(o1)[N+]([O-])=O | 0.25g | 718057990
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Medchemexpress LLC HY-111388A 10mg Medchemexpress, SEL120-34A (monohydrochloride) CAS: Purity:>98%
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Medchemexpress, HY-111388A 10mg SEL120-34A (monoHCl) CAS: SEL120-34A monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8. SEL120-34A monohydrochloride weakly inhibits CDK9 (calculated IC50=1070 nM), but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. SEL120-34A monohydrochloride inhibits phosphorylation of STAT1 S727 and STAT5 S726. Has anti-tumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111388A 5mg Medchemexpress, SEL120-34A (monohydrochloride) CAS: Purity:>98%
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Medchemexpress, HY-111388A 5mg SEL120-34A (monoHCl) CAS: SEL120-34A monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8. SEL120-34A monohydrochloride weakly inhibits CDK9 (calculated IC50=1070 nM), but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. SEL120-34A monohydrochloride inhibits phosphorylation of STAT1 S727 and STAT5 S726. Has anti-tumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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MEDCHEMEXPRESS LLC KINESORE 5MG
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501872427 KINESORE 5MG
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Aobchem 1 2 3-Tribromobenzene | ≥97% | CAS 608-21-9 | C6H3Br3 | 10g
1 2 3-Tribromobenzene | ≥97% | CAS 608-21-9 | C6H3Br3 | 10g
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MEDCHEMEXPRESS LLC AZ3451 5MG
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501872396 AZ3451 5MG
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MEDCHEMEXPRESS LLC H-89 DIHYDROCHLORIDE 10MG
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501873404 H-89 DIHYDROCHLORIDE 10MG
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MEDCHEMEXPRESS LLC SMER28 5MG
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501871677 SMER28 5MG
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Aobchem 1-Benzyl-2-bromobenzene | ≥95% | CAS 23450-18-2 | C13H11Br | 5g
1-Benzyl-2-bromobenzene | ≥95% | CAS 23450-18-2 | C13H11Br | 5g
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Aobchem 1-Benzyl-2-bromobenzene | ≥95% | CAS 23450-18-2 | C13H11Br | 1g
1-Benzyl-2-bromobenzene | ≥95% | CAS 23450-18-2 | C13H11Br | 1g
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Aobchem 1-Benzylthio-4-bromobenzene | ≥97% | CAS 53136-21-3 | C13H11BrS | 10g
1-Benzylthio-4-bromobenzene | ≥97% | CAS 53136-21-3 | C13H11BrS | 10g
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Medchemexpress LLC HY-101855 5mg Medchemexpress, Anle138b CAS:882697-00-9 Purity:>98%
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Medchemexpress, HY-101855 5mg Anle138b CAS:882697-00-9 Anle138b is an oligomeric aggregation inhibitor. Anle138b is an oligomer modulator for neurodegenerative diseases such Parkinson's disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-125276 5mg Medchemexpress, TH5487 CAS:2304947-71-3 Purity:>98%
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Medchemexpress, HY-125276 5mg TH5487 CAS:2304947-71-3 TH5487 is a potent 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC50 of 342 nM. TH5487 stops OGG1 from recognizing its DNA substrate, inhibits DNA repair and modifies OGG1 chromatin dynamics, which results in the inhibition of proinflammatory pathway genes. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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