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Filtered Search Results
Medchemexpress LLC (2S)-2-[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)imidazo[4,5-b]pyridin-2-yl]methylamino]propanamide | 1233231-30-5 | 98.3% | 419.4 g/mol | C20H20F3N5O2 | 25MG
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DSP-2230 (ANP-230) is an orally active voltage-gated sodium channel inhibitor used in preclinical research to modulate Nav1.7, Nav1.8, and Nav1.9 activity and to evaluate approaches for neuropathic pain. The compound is supplied as a solid with characterized solubility profiles and storage recommendations for laboratory use only.
- Inhibits Nav1.7, Nav1.8, and Nav1.9 with reported IC50s of 7.1 μM, 11.4 μM, and 6.7 μM respectively.
- Reported purity 98.33%.
- Soluble in DMSO at ≥100 mg/mL; multiple in vivo formulation protocols with solubility ≥2.25 mg/mL are provided.
- Powder stability: -20°C for up to 3 years; solution stability conditions are reported.
- Intended for preclinical studies of sodium channel pharmacology and neuropathic pain models.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379885 CE3F4 ANALOG 1 50MG
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eMolecules Ethyl 4-(4-bromophenyl)-2,4-dioxobutanoate | 40155-54-2 | MFCD03411525 | 1g
Combi-Blocks | Ethyl 4-(4-bromophenyl)-2,4-dioxobutanoate | 1g | 205384234 | HC-3913 | 98.000 | 40155-54-2 | MFCD03411525 | 299.120 | C12H11BrO4
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Selleck Chemical LLC IDO-IN-1
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IDO-IN-1 is a potent indoleamine 2 3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM
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Medchemexpress LLC 8-bromo-4H-oxadiazolo[3,4-c]benzoxazin-1-one | 204326-43-2 | 99.6% | 269.05 g/mol | C9H5BrN2O3 | 50MG
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NS-2028 is a selective soluble guanylyl cyclase (sGC) inhibitor used in biochemical and cellular research to probe sGC signaling. It inhibits basal sGC activity with an IC50 of about 30 nM and NO-stimulated activity with an IC50 of about 200 nM. The compound is supplied in solid form or as a DMSO solution to support diverse experimental workflows.
- Highly selective soluble guanylyl cyclase inhibitor for pathway interrogation.
- High potency: IC50 ≈ 30 nM (basal) and ≈ 200 nM (NO-stimulated).
- Suitable for biochemical and cell-based assays.
- Available as solid and as DMSO solution formats for flexible dosing.
- Molecular weight 269.05 g/mol and formula C9H5BrN2O3 for reference.
- High purity suitable for research applications.
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Aobchem 3-Bromophenylboronic acid, AOBCHEM USA 10307-25G. 89598-96-9. MFCD00239386
3-Bromophenylboronic acid, AOBCHEM USA 10307-25G. 89598-96-9. MFCD00239386
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Medchemexpress LLC CP-547632 hydrochloride | 252003-71-7 | MFCD20268381 | 99.9% | C20H25BrClF2N5O3S | 10MG
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CP-547632 hydrochloride is the hydrochloride salt form of a potent, orally active ATP-competitive inhibitor of VEGFR-2 and FGF kinases, with reported IC50 values of 11 nM and 9 nM, respectively. It demonstrates selectivity versus EGFR and PDGFRβ and has shown antitumor efficacy in preclinical models.
- ATP-competitive VEGFR-2 and FGF kinase inhibition.
- Low-nanomolar potency (IC50s ≈11 nM and ≈9 nM).
- Selective profile versus related tyrosine kinases.
- Suitable for in vitro and in vivo preclinical studies.
- High supplied purity (~99.9%).
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eMolecules 2-Chloro-4-trifluoromethoxyphenol | 70783-75-4 | MFCD04972753 | 1g
Oakwood Chemical | 2-Chloro-4-trifluoromethoxyphenol | 1g | 537682813 | 024882 | | 70783-75-4 | MFCD04972753 | 212.550 | C7H4ClF3O2
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eMolecules 2-Bromophenylboronic acid mida ester | 943552-28-1 | MFCD11215210 | 5g
Combi-Blocks | 2-Bromophenylboronic acid mida ester | 5g | 401044077 | QH-8672 | 95.000 | 943552-28-1 | MFCD11215210 | 311.930 | C11H11BBrNO4
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Apexbio Technology LLC Brimonidine Tartrate 70359-46-5 50mg
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Brimonidine tartrate (CAS 70359-46-5) is a selective agonist of the -adrenergic receptor By activating these receptors it inhibits adenylyl cyclase activity resulting in decreased intracellular cyclic AMP (cAMP) levels This modulation reduces sympathetic neural activity lowers aqueous humor production and enhances uveoscleral outflow in ocular tissues Brimonidine tartrate is widely employed in research on glaucoma and ocular hypertension and serves as a standard tool in studies investigating -adrenergic signaling and autonomic nervous system regulation
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eMolecules 4-Bromo-6-(trifluoromethoxy)quinoline | 1189105-68-7 | MFCD12674963 | 1g
Combi-Blocks | 4-Bromo-6-(trifluoromethoxy)quinoline | 1g | 335348478 | LD-1585 | 95.000 | 1189105-68-7 | MFCD12674963 | 292.055 | C10H5BrF3NO
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eMolecules 2-(2-Bromophenyl)ethanethioamide | 103317-32-4 | MFCD09816252 | 1g
Combi-Blocks | 2-(2-Bromophenyl)ethanethioamide | 1g | 232304073 | HC-4062 | 95.000 | 103317-32-4 | MFCD09816252 | 230.120 | C8H8BrNS
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eMolecules 3-Bromo-5-fluoroaniline HCl | 134168-98-2 | MFCD09800744 | 1g
Combi-Blocks | 3-Bromo-5-fluoroaniline HCl | 1g | 232301499 | AN-3437 | 98.000 | 134168-98-2 | MFCD09800744 | 226.470 | C6H6BrClFN
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eMolecules 4-Bromo-2,3-Dichloroaniline | 56978-48-4 | MFCD01764744 | 1g
Chem-Impex | 4-Bromo-2,3-Dichloroaniline | 1g | 386898239 | 23418 | | 56978-48-4 | MFCD01764744 | 240.910 | C6H4BrCl2N
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eMolecules BENZENE-1,3,5-TRIYLTRIBORONIC ACID | 89641-21-4 | MFCD20275289 | 1g
AstaTech | BENZENE-1,3,5-TRIYLTRIBORONIC ACID | 1g | 296379368 | F11883 | 95.000 | 89641-21-4 | MFCD20275289 | 209.560 | C6H9B3O6
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