The BioFire JI Control Panel M420 is intended for use as an external positive and negative assayed quality control to monitor the performance of in vitro laboratory nucleic acid testing procedures for the qualitative detection of gram-positive and gram-negative bacteria on the BioFire Joint Infection (JI) Panel on the BioFire systems. BioFire JI Control Panel M420 is comprised of 2 controls, BioFire JI Positive Control and BioFire JI Negative Control. BioFire JI Control Panel M420 is comprised of 12 single use tubes, 6 tubes of positive control and 6 tubes of negative control, 200μL each. BioFire JI Positive Control contains synthetic DNA suspended in a non-infectious solution of buffers, preservatives and stabilizers. BioFire JI Negative Control contains buffers and preservatives.