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Filtered Search Results
Apexbio Technology LLC SB-3CT 5MG
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502240480 SB-3CT 5MG
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Medchemexpress LLC HY-13455A 5mg Medchemexpress, LDN-192960 (hydrochloride) CAS:2309172-48-1 Purity:>98%
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Medchemexpress, HY-13455A 5mg LDN-192960 (HCl) CAS:2309172-48-1 LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1206248-77-2 | 5-Fluorothiazolo[4,5-b]pyridin-2-amine | MFCD14581837 | 100mg
ChemScene | tert-Butyl (3-((5-bromopyrimidin-2-yl)amino)propyl)carbamate | 100mg | 768994411 | CS-0619756 | 1289003-99-1 | MFCD29113426 | 331.214 | C12H19BrN4O2
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Medchemexpress LLC Mps1-IN-3 hydrochloride | 2989453-29-2 | 98.0% | 574.09 g/mol | C26H32ClN7O4S | 5MG
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Mps1-IN-3 hydrochloride is a potent and selective Mps1 (TTK) kinase inhibitor (IC50 ≈ 50 nM) supplied as a research-grade hydrochloride salt. It inhibits proliferation of glioblastoma cells and can sensitize glioblastoma xenografts to vincristine, making it suitable for cell biology and cancer-kinase studies. Provided as a solid with high purity for in vitro research.
- Potent Mps1 kinase inhibitor (IC50 ≈ 50 nM).
- Supplied as hydrochloride salt, solid form.
- High purity (98.0%).
- Molecular weight 574.09 g/mol; formula C26H32ClN7O4S.
- CAS 2989453-29-2.
- Available in small-scale laboratory package sizes for research use.
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Medchemexpress LLC HY-N7128 100mg Medchemexpress, Flavanone CAS:487-26-3 Purity:>98%
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Medchemexpress, HY-N7128 100mg Flavanone CAS:487-26-3 Flavanone is used to characterize the authenticity of lemon juice by monitoring of flavanone content. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 313261-56-2 | N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide | Oakwood Chemicals | MFCD00987159 | 396.470 | C20H20N4O3S | 95.000 | Cc1cccc(c1)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(C)n1 | 10mg | 480151963
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide | Oakwood Chemicals | 313261-56-2 | MFCD00987159 | 396.470 | C20H20N4O3S | 95.000 | Cc1cccc(c1)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nc(C)cc(C)n1 | 10mg | 480151963
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Medchemexpress LLC HY-101676 5mg Medchemexpress, RG-12525 CAS:120128-20-3 Purity:>98%
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Medchemexpress, HY-101676 5mg RG-12525 CAS:120128-20-3 RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 µM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-B0290A 100mg Medchemexpress, Pranlukast (hemihydrate) CAS:150821-03-7 Purity:>98%
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Medchemexpress, HY-B0290A 100mg Pranlukast (hemihydrate) CAS:150821-03-7 Pranlukast hemihydrate is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 183320-51-6 | Medchem Express | Desmethyl Erlotinib (hydrochloride) | 5mg | 446262581 | HY-13256 | MFCD22420811 | 415.87 | C21H22ClN3O4
Ambeed | N-(3-Fluoro-4-(4455-tetramethyl-132-dioxaborolan-2-yl)benzyl)cyclohexanamine hydrochloride | 250mg | 718339297 | A1627726 | 2828446-31-5 | 369.710 | C19H30BClFNO2
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Medchemexpress LLC HY-111445 5mg Medchemexpress, CeMMEC1 CAS:440662-09-9 Purity:>98%
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Medchemexpress, HY-111445 5mg CeMMEC1 CAS:440662-09-9 CeMMEC1 is an inhibitor of BRD4, and also has high affinity for TAF1, with an IC50 of 0.9 μM for TAF1, and a Kd of 1.8 μM for TAF1 (2). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Jak3-in-6 | 1443235-95-7 | 99.9% | 350.37 | C19H18N4O3 | 50 MG
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JAK3-IN-6 is a potent, selective, irreversible inhibitor of Janus associated kinase 3 (JAK3) with sub-nanomolar potency, provided as a solid for research use. It exhibits well-defined solubility and purity suitable for in vitro and in vivo experiments.
- Potent, selective irreversible JAK3 inhibitor (IC50 0.15 nM).
- High purity (99.9%).
- Soluble in DMSO (100 mg/mL); in vivo formulations ≥2.17 mg/mL.
- White to light yellow solid appearance.
- Available in multiple pack sizes and DMSO solution formats.
- Suitable for biochemical and cellular studies of JAK/STAT signaling.
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Apexbio Technology LLC Icotinib 610798-31-7 5mg
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Icotinib (CAS 610798-31-7) is a small molecule inhibitor targeting the epidermal growth factor receptor (EGFR) tyrosine kinase exhibiting an in vitro IC50 of 5 nM EGFR a transmembrane tyrosine kinase receptor plays a central role in cell proliferation motility and apoptosis and is overexpressed in various cancers including non-small cell lung cancer (NSCLC) breast ovarian and head and neck cancers Icotinib inhibits EGF-induced EGFR phosphorylation and downstream tyrosine phosphorylation of intracellular proteins in human carcinoma A431 cells in a dose-dependent manner In animal models icotinib suppresses tumor growth without significant toxicity It is of interest for preclinical and clinical research on EGFR-driven malignancies
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Medchemexpress LLC N-Demethyl Ivabradine hydrochloride | 1246638-08-3 | 99.6% | 1 MG
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N-Demethyl Ivabradine HCl is a metabolite of Ivabradine, which is a specific inhibitor of the funny channel. It is for research use only.
- Specific inhibitor of the funny channel
- White to off-white solid appearance
- Soluble in DMSO
- Store at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC HY-101492 5mg Medchemexpress, GPR120-IN-1 CAS:1599477-75-4 Purity:>98%
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Medchemexpress, HY-101492 5mg GPR120-IN-1 CAS:1599477-75-4 GPR120-IN-1 is a selective Gpr120 agonist with a logEC 50 of −7.62. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 10 MM 1 ML
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Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3. This compound exhibits antitumor efficacy.
- Selective, orally active inhibitor for VEGFR-1, 2, and 3
- Exhibits antitumor efficacy
- Available in solid form, white to off-white color
- Soluble in DMSO (125 mg/mL)
- Inhibits the phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3
- Inhibits VEGF-induced proliferation and migration of HUVECs
- Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells
- Exhibits antitumor efficacy against various cancers in athymic mice models
- Reversibly suppresses vascular permeability and angiogenesis in tumor-bearing rats
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