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Filtered Search Results
Medchemexpress LLC KRAS G12C inhibitor 15 | 2349393-21-9 | 98.5% | 498.91 | C25H21ClF2N4O3 | 10MG
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KRAS G12C inhibitor 15 is a potent small-molecule inhibitor of the oncogenic KRAS G12C mutant, reported from patent WO2019110751A1 (compound 22). It is supplied as a high-purity solid and as a DMSO solution for research use, and biochemical assays report an IC50 of 5 nM for KRAS G12C.
- Potent KRAS G12C inhibition (IC50 = 5 nM).
- High purity, 98.5%.
- Molecular weight 498.91 and formula C25H21ClF2N4O3.
- Available in small solid quantities and as a 10 mM solution in DMSO.
- Suitable for biochemical and cell-based research applications.
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Accela Chembio Inc 4-(trifluoromethoxy)benzoic Acid | 25g | 330-12-1 | MFCD00002541 | 97+% | Shelf Life: 1260 Days | Regular
4-(trifluoromethoxy)benzoic Acid | 25g | 330-12-1 | MFCD00002541 | 97+% | Shelf Life: 1260 Days | Regular
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Apexbio Technology LLC LY2606368 5MG
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502240112 LY2606368 5MG
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eMolecules Medchem Express / CGP 36742 / 5mg / 485251386 / HY-121599 / / 123690-78-8 / MFCD00882735 / 179.200 / C7H18NO2P
Medchem Express / CGP 36742 / 5mg / 485251386 / HY-121599 / / 123690-78-8 / MFCD00882735 / 179.200 / C7H18NO2P
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eMolecules 3-Methoxy-5-methylpyrazin-2-amine | 89464-87-9 | MFCD09750038 | 1g
Combi-Blocks, Inc. | 3-Methoxy-5-methylpyrazin-2-amine | 1g | 569293461 | QP-7071 | 98.000 | 89464-87-9 | MFCD09750038 | 139.158 | C6H9N3O
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Medchemexpress LLC Bay-320 | 1445830-50-1 | MFCD31657346 | 99.7% | 492.52 g/mol | C26H26F2N6O2 | 50 MG
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BAY-320 is a selective, ATP-competitive inhibitor of the Bub1 kinase used in biochemical and cellular research. It inhibits Bub1 catalytic activity (IC50 ≈ 680 nM), disrupts Bub1-mediated Sgo1 localization, alters mitotic chromosome arrangement and spindle assembly, and reduces cell proliferation, making it useful in cancer research applications such as studies of ovarian and cervical cancer.
- Selective ATP-competitive Bub1 kinase inhibitor
- Biochemical and cellular activity with reported IC50 ≈ 680 nM
- Disrupts Sgo1 localization and mitotic chromosome arrangement
- Available as powder and as a 10 mM solution in DMSO for flexible use
- High purity suitable for research applications
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Medchemexpress LLC HY-107337 10mg Medchemexpress, Delapril (hydrochloride) CAS:83435-67-0 Purity:>98%
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Medchemexpress, HY-107337 10mg Delapril (HCl) CAS:83435-67-0 Delapril is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![Medchemexpress LLC 5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1,3,4-thiadiazol-2-amine | 40045-50-9 | MFCD01927019 | 98.9% | 261.3 g/mol | C5H3N5O2S3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240708.png-250.jpg)
Medchemexpress LLC 5-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1,3,4-thiadiazol-2-amine | 40045-50-9 | MFCD01927019 | 98.9% | 261.3 g/mol | C5H3N5O2S3 | 10 MG
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Halicin (SU3327) is a small-molecule c-Jun N-terminal kinase (JNK) inhibitor provided for laboratory research use. It demonstrates activity against JNK1 (IC50 = 0.7 μM) and disrupts the JNK-JIP protein-protein interaction (IC50 = 239 nM); available in multiple solid and solution formats with reported high purity.
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Medchemexpress LLC (R)-zanubrutinib | 1691249-44-1 | MFCD31567462 | 99.0% | 471.5 g/mol | C27H29N5O3 | 25 MG
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(R)-Zanubrutinib is the R enantiomer of zanubrutinib, a selective inhibitor of Bruton's tyrosine kinase (BTK). It is provided as a high-purity research compound for biochemical assays and preclinical studies focused on BTK signaling and inhibition.
- High purity suitable for biochemical assays.
- Potent BTK inhibition (IC50 11 nM).
- Available in small research pack sizes for preclinical work.
- Useful for target validation and signaling pathway studies.
- Provided with SDS and CAS registry information for traceability.
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Apexbio Technology LLC PND-1186 10MM IN 1ML DMSO
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PND-1186 10MM IN 1ML DMSO APEXBIO TECHNOLOGIES
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Medchemexpress LLC Tp-004 | 1454299-21-8 | 99.2% | 5 MG
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TP-004 is a potent, reversible inhibitor of methionine aminopeptidase 2 (MetAP2) with an IC50 of 6 nM, supplied as a light yellow to khaki solid for research use.
- Potent reversible MetAP2 inhibitor, IC50 6 nM.
- Molecular weight 363.34 g/mol; formula C17H16F3N5O.
- High purity, 99.17% (analytical).
- Soluble in DMSO (~250 mg/mL); may require ultrasonic agitation.
- Available in small solid quantities including 5 mg.
- Store powder at -20°C for long-term stability.
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Medchemexpress LLC HY-12758A 5mg Medchemexpress, YHO-13351 (free base) CAS:912288-64-3 Purity:>98%
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Medchemexpress, HY-12758A 5mg YHO-13351 (free base) CAS:912288-64-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules Broadpharm / Nutlin-3 / 10mg / 686680979 / BP-27838 / / 548472-68-0 / [null] / 581.490 / C30H30Cl2N4O4](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464853.JPG-250.jpg)
eMolecules Broadpharm / Nutlin-3 / 10mg / 686680979 / BP-27838 / / 548472-68-0 / [null] / 581.490 / C30H30Cl2N4O4
Broadpharm / Nutlin-3 / 10mg / 686680979 / BP-27838 / / 548472-68-0 / [null] / 581.490 / C30H30Cl2N4O4
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Medchemexpress LLC Rg-12525 | 120128-20-3 | 98.3% | 423.47 g/mol | C25H21N5O2 | 50 MG
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RG-12525 (NID 525) is a small-molecule research compound that antagonizes peptidoleukotriene receptors (LTC4, LTD4, LTE4), exhibits PPAR-γ agonist activity, and inhibits cytochrome P450 enzymes. It is provided in high-purity solid form and as a DMSO solution for biochemical and pharmacological research, supporting both in vitro and in vivo investigations.
- Potent leukotriene receptor antagonist with low-nanomolar activity.
- Shows PPAR-γ agonist activity (≈60 nM).
- Inhibits CYP3A4 (Ki ≈0.5 μM), useful for metabolism studies.
- Available as solid and DMSO solution for flexible dosing.
- High purity suitable for biochemical and pharmacological assays.
- Applicable to in vitro and in vivo pharmacology research.
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Apexbio Technology LLC Doxepin (hydrochloride) 1229-29-4 5g
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Doxepin (hydrochloride) (CAS 1229-29-4) is a tricyclic antidepressant that functions as a potent antagonist of the histamine H1 receptor a G protein coupled receptor expressed in tissues such as smooth muscle vascular endothelium cardiac tissue and the central nervous system In vitro doxepin acts as a competitive inhibitor of serotonin uptake in human platelets with a reported Ki of approximately 0 2 M and can induce rapid serotonin efflux at higher concentrations In vivo studies in rodents and canines demonstrate efficient oral absorption and metabolic conversion in liver and urine with central nervous system penetration observed in rats Doxepin is widely used in research related to neurotransmitter modulation and histaminergic signaling
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