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Filtered Search Results
Medchemexpress LLC GB-110 hydrochloride | 99.86% | 645.23 | 50 MG
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GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. It selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM.
- Potent
- Orally active
- Nonpeptidic protease activated receptor 2 (PAR2) agonist
- Selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM
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eMolecules Medchem Express / Pocapavir / 5mg / 446258561 / HY-104074 / / 146949-21-5 / MFCD00950032 / 423.710 / C21H17Cl3O3
Medchem Express / Pocapavir / 5mg / 446258561 / HY-104074 / / 146949-21-5 / MFCD00950032 / 423.710 / C21H17Cl3O3
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Medchemexpress LLC GSK2945 (hydrochloride) | 98.5% | 457.80 | 50 MG
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GSK2945 hydrochloride is a tertiary amine and a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist. It has EC50s of 21.5 μM and 20.8 μM, respectively. This compound functions by enhancing cholesterol 7α-hydroxylase (CYP7A1) levels and promoting cholesterol metabolism.
- Highly specific antagonist.
- Enhances cholesterol 7α-hydroxylase levels.
- Promotes cholesterol metabolism.
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eMolecules Medchem Express / RU 24969 / 5mg / 446267669 / HY-16688 / / 66611-26-5 / MFCD09864704 / 228.295 / C14H16N2O
Medchem Express / RU 24969 / 5mg / 446267669 / HY-16688 / / 66611-26-5 / MFCD09864704 / 228.295 / C14H16N2O
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eMolecules Medchem Express / Zardaverine / 5mg / 446265785 / HY-15485 / / 101975-10-4 / MFCD00867059 / 268.220 / C12H10F2N2O3
Medchem Express / Zardaverine / 5mg / 446265785 / HY-15485 / / 101975-10-4 / MFCD00867059 / 268.220 / C12H10F2N2O3
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![eMolecules Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502449217.PNG-250.jpg)
eMolecules Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S
Medchem Express / Rogaratinib / 1mg / 446254781 / HY-100019 / / 1443530-05-9 / [null] / 466.560 / C23H26N6O3S
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eMolecules Medchem Express / SU3327 / 5mg / 518570903 / HY-107597 / / 40045-50-9 / MFCD01927019 / 261.290 / C5H3N5O2S3
Medchem Express / SU3327 / 5mg / 518570903 / HY-107597 / / 40045-50-9 / MFCD01927019 / 261.290 / C5H3N5O2S3
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eMolecules Medchem Express / YK-3-237 / 5mg / 686921889 / HY-19634 / / 1215281-19-8 / MFCD28167612 / 372.180 / C19H21BO7
Medchem Express / YK-3-237 / 5mg / 686921889 / HY-19634 / / 1215281-19-8 / MFCD28167612 / 372.180 / C19H21BO7
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Medchemexpress LLC BRD4 Inhibitor-24 | 309951-18-6 | 99.27% | 262.26 | 50 MG
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BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor that has demonstrated antitumor activity. It shows IC50 values of 33.7 μM against MCF7 cells and 45.9 μM against K652 cells. This compound has been extracted from patent CN107721975A.
- Potent BRD4 inhibitor.
- Exhibits antitumor activity against MCF7 (IC50: 33.7 μM) and K652 (IC50: 45.9 μM) cells.
- Derived from patent CN107721975A.
- For research use only.
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Enzo Life Sciences 4-Phenylchalcone Oxide (100mg). CAS: 82389-34-2
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Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml). Long Term Storage: -20°C.
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Medchemexpress LLC Ipriflavone | 35212-22-7 | MFCD00221719 | >98.0% | 280.32 | 500 MG
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Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. It is intended for research and analytical applications.
- Targets cytochrome P450.
- Relevant to research in metabolic disease.
- Relevant to research in cancer.
- Functions to suppress bone resorption.
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Selleck Chemical LLC ONO-4059 analogue
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ONO-4059 analogue (ONO-WG-307) is an analogue of ONO-4059 which is a highly potent and selective oral BTK inhibitor with IC50 of 23 9 nM Phase 1
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Selleck Chemical LLC Genz-123346 free base
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Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1 the first step in the biosynthesis of gangliosides and other glycosphingolipids
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eMolecules ChemScene / 5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine / 100mg / 632319307 / CS-0119828 / 0.000 / 852443-66-4 / MFCD20724093 / 153.185 / C7H11N3O
ChemScene / 5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine / 100mg / 632319307 / CS-0119828 / 0.000 / 852443-66-4 / MFCD20724093 / 153.185 / C7H11N3O
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Medchemexpress LLC PXS-5153A (monohydrochloride) | 2125956-82-1 | 99.6% | 438.95 | 50 MG
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PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorate fibrosis.
- Exhibits an IC50 of <40 nM for LOXL2 across all mammalian species tested.
- Also inhibits human LOXL3 with an IC50 value of 63 nM.
- Is >40-fold selective for LOXL2 over both LOX and LOXL1 and >700-fold selective over other related amine oxidases.
- Is a fast acting inhibitor, with enzymatic activity almost entirely blocked within 15 minutes.
- Reduces crosslinks and ameliorates fibrosis.
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