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Filtered Search Results
Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | C25H27ClF3N5O3 | 10MG
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PND-1186 hydrochloride is the hydrochloride salt of a potent, selective, and reversible focal adhesion kinase (FAK) inhibitor supplied for laboratory research. It exhibits nanomolar potency (IC50 = 1.5 nM) and selectively promotes tumor cell apoptosis. Supplied as a high-purity solid with defined solubility and storage recommendations for controlled experimental use.
- Potent FAK inhibition with IC50 of 1.5 nM.
- High purity (99.9%).
- Molecular formula C25H27ClF3N5O3; molecular weight 537.96.
- Soluble in DMSO (100 mg/mL) and water (20 mg/mL).
- Recommended storage: 4°C for solid; in solvent -80°C up to 6 months.
- Intended for research use only; not for human or veterinary use.
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Medchemexpress LLC HY-101106 5mg Medchemexpress, AR7 CAS:80306-38-3 Purity:>98%
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Medchemexpress, HY-101106 5mg AR7 CAS:80306-38-3 AR7 is a retinoic acid receptor α ( RARα ) antagonist. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-101056 5mg Medchemexpress, AZD7986 CAS:1802148-05-5 Purity:>98%
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Medchemexpress, HY-101056 5mg AZD7986 CAS:1802148-05-5 AZD7986 is a Dipeptidyl peptidase 1 ( DPP1 ) inhibitor with pIC 50 s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Diphenyl phosphoryl chloride | 2524-64-3 | MFCD00003030 | 100 g
Diphenyl phosphoryl chloride | Purity: 99% | Mol Wt: 268.63 | 2524-64-3 | MFCD00003030 | 100 g
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Medchemexpress LLC Grp-60367 hydrochloride | 2803211-60-9 | 99.4% | C21H28ClN3O2 | 10MG
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GRP-60367 hydrochloride is the hydrochloride salt of a small-molecule rabies virus (RABV) inhibitor intended for laboratory research. The compound is supplied in multiple milligram quantities and is suitable for in vitro antiviral screening and mechanistic studies.
- High purity (99.4%).
- Hydrochloride salt form improves handling and solubility.
- Available in multiple small-mass pack sizes for screening experiments.
- Well-characterized molecular properties for reproducible research.
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Medchemexpress LLC (R)-verapamil hydrochloride | 38176-02-2 | MFCD00069355 | 99.4% | C27H39ClN2O4 | 10MG
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(R)-Verapamil hydrochloride is the R-enantiomer of verapamil presented as the hydrochloride salt. It is used as a research reagent to study L-type calcium channel inhibition and modulation of drug transporters such as P-glycoprotein/MRP1. The material is supplied as a solid with high reported purity suitable for biochemical and pharmacological assays.
- High chemical purity, 99.4% by manufacturer.
- R-enantiomer for stereospecific pharmacological studies.
- Solid form suitable for long-term storage and handling.
- Suitable for studies of calcium channel activity and transporter modulation.
- Available in small lab-scale package sizes for research use.
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Medchemexpress LLC HY-16500 5mg Medchemexpress, Tolrestat CAS:82964-04-3 Purity:>98%
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Medchemexpress, HY-16500 5mg Tolrestat CAS:82964-04-3 Tolrestat is a potent, orally active aldose reductase inhibitor with IC50 of 35 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC ETRUMADENANT 100MG
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Etrumadenant | Purity: 98% | 2239273-34-6 | 100mg
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Medchemexpress LLC Prexasertib dimesylate | 1234015-58-7 | MFCD32693943 | 98.9% | 557.60 | C20H27N7O8S2 | 10 MG
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Prexasertib dimesylate is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor supplied as a solid research compound. It causes double-stranded DNA breakage and replication catastrophe that lead to apoptosis, and is offered in multiple solid pack sizes and solution formats for laboratory use. Not for human or clinical use.
- Selective ATP-competitive CHK1 inhibitor.
- Induces DNA double-strand breaks and replication catastrophe.
- High purity: 98.9%.
- Available as solid and as 10 mM solution in DMSO.
- Solubility data provided for in vitro and in vivo protocols.
- Recommended storage: 4°C (solid) and -80°C for stock solutions.
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Medchemexpress LLC Apabetalone | 1044870-39-4 | 99.34% | 370.40 | 100 MG
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Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators, specifically targeting the second bromodomain (BD2) with high selectivity. It enhances the production of ApoA-I in hepatocytes, leading to an increase in high-density lipoprotein cholesterol (HDL-C). Its mechanism involves binding to bromodomains of the BET family by competing for acetylated lysine binding sites. This epigenetic modulation of ApoA-I production suggests it as a potential therapeutic agent for atherosclerosis.
- Selective BET transcriptional regulator inhibitor
- Targets the second bromodomain (BD2)
- Increases ApoA-I production in liver cells
- Elevates high-density lipoprotein cholesterol (HDL-C)
- Acts via an epigenetic mechanism
- Investigated for atherosclerosis treatment
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Sigma Aldrich Fine Chemicals Biosciences Roflumilast >=98% (HPLC) | 162401-32-3 | MFCD00938270 | 10MG
Roflumilast >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 403.21 | 162401-32-3 | MFCD00938270 | 10MG
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Medchemexpress LLC S-verapamil hydrochloride | 36622-28-3 | MFCD11045898 | 98.3% | C27H39ClN2O4 | 10MG
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(S)-Verapamil hydrochloride is the S-enantiomer of the calcium channel blocker verapamil, supplied as the hydrochloride salt for use in pharmacology and transporter research. It is reported to inhibit leukotriene C4 (LTC4) and calcein transport by the multidrug resistance protein MRP1 and is provided as a high-purity research reagent.
- Enantiomer-specific activity useful for stereoselective studies.
- Suitable for transporter and pharmacology assays.
- Hydrochloride salt form improves solubility in polar solvents.
- Reported inhibition of LTC4 and MRP1-mediated transport.
- High purity (98.3%) for reproducible experimental results.
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Chemical Diversity Labs Inc N-6-CHLORO7HYDROXY5METHYL 10MG
CHEMICAL DIVERSITY LABS INC|N-{6-CHLORO-7-HYDROXY-5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL}CYCLOHEXANECARBOXAMIDE|10mg|D205-0264|309.76
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Medchemexpress LLC HY-10997 50mg Medchemexpress, Ibrutinib CAS:936563-96-1 Purity:>98%
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Medchemexpress, HY-10997 50mg Ibrutinib CAS:936563-96-1 Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Rivastigmine S4687-20mg
Rivastigmine (SDZ-ENA 713 Exelon) is a cholinesterase inhibitor with IC50 of 5 5 M It inhibits acetylcholinesterase (IC50 4 15 M) and butyrylcholinesterase (IC50 37 nM)
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