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Organic compounds that consist of a phenyl group with a carboxylic acid group substitution; a carboxylic acid contains a carbon atom bonded to both a carbonyl group and a hydroxyl group.
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Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR) Evocalcet (0 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2 ] concentrations with an EC50 value of 92 7 nM in hCaR-HEK293 cells
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