Phenylcarbamic acid esters
Medchemexpress LLC 10-((tert-butoxycarbonyl)amino)decanoic acid | 173606-50-3 | MFCD00270351 | >98.0% | 287.40 g·mol⁻¹ | C15H29NO4 | 25 G
Boc-10-aminodecanoic acid (10-((tert-butoxycarbonyl)amino)decanoic acid) is a Boc-protected amino acid used as a linker building block in peptide synthesis and PROTAC construction. It contains a terminal carboxylic acid and a Boc-protected amine that enable standard coupling reactions and selective deprotection.
- Boc-protected amino acid with terminal carboxylic acid.
- Suitable for peptide synthesis and PROTAC linker construction.
- High purity for research applications.
- Soluble in common organic solvents for coupling chemistry.
- Available in multiple pack sizes, including 25 g.
Medchemexpress LLC Bromo-PEG2-C2-Boc | 1381861-91-1 | 97.0% | C11H21BrO4 | 10 G
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs are compounds designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein.
- PEG-based linker for PROTAC synthesis
- Utilizes the ubiquitin-proteasome system
- Designed for selective degradation of target proteins
Medchemexpress LLC Acid-C1-PEG5-Boc | 2304558-22-1 | 97.0% | C17H32O9 | 100 MG
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Colorless to light yellow liquid
Medchemexpress LLC 5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(1,1-dimethylethyl) ester | 1347750-75-7 | 99.6% | C14H27NO7 | 1 G
Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Peg-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC N-Nornuciferine | 4846-19-9 | 1 ML
N-Nornuciferine is an aporphine alkaloid derived from lotus leaf. It is known for its significant inhibitory activity against the CYP2D6 enzyme, with IC50 and Ki values of 3.76 μM and 2.34 μM, respectively.
- Derived from lotus leaf
- Selectively inhibits CYP2D6 activity
- Shows weak or no inhibition of other P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9)
- Competitively inhibits dextromethorphan o-demethylation
Medchemexpress LLC Carbamic acid, N-(4-bromobutyl)-, 1,1-dimethylethyl ester | 164365-88-2 | 252.15 | 10 G
Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize the ubiquitin-proteasome system
- Target protein degradation
Medchemexpress LLC N-Acetyldesloratadin 1mg | 117796-52-8 | 1 MG
N-acetyldesloratadine is a research reagent that functions as a dual antagonist of platelet-activating factor (PAF) and histamine. It inhibits PAF-induced aggregation of human platelets (IC50 ≈ 0.6 μM) and is used in studies of allergic disease, platelet aggregation, and inflammation-related signaling. The compound is a white to off-white solid with molecular formula C21H21ClN2O and molecular weight 352.86.
