Phenylcarbamic acid esters
Medchemexpress LLC N-Boc-L-Prolinal | 69610-41-9 | 98.8% | C10H17NO3 | 25 G
N-Boc-L-Prolinal is a proline derivative featuring a Boc protecting group, commonly employed in the synthesis of biologically active peptide mimetics. This compound is primarily intended for research applications, including the development of Dolastatin 10 analogs that exhibit anti-colon cancer activity.
- Proline derivative with a Boc protecting group
- Used in the synthesis of biologically active peptide mimetics
- Applied in the development of Dolastatin 10 analogs
- Analogs demonstrate anti-colon cancer activity
- Intended for research use only
Medchemexpress LLC 5,8,11-trioxa-2-azatridecanoic acid, 13-hydroxy-, 1,1-dimethylethyl ester | 106984-09-2 | 99.5% | 293.36 g·mol⁻¹ | C13H27NO6 | 25 G
Boc-NH-PEG4 is a PEG-based linker containing a Boc-protected amine, designed as a hydrophilic, flexible spacer for use in the synthesis of PROTACs and other bifunctional conjugates. It facilitates modular assembly and conjugation chemistry in medicinal chemistry workflows.
- PEG spacer increases solubility and flexibility.
- Boc-protected amine enables selective deprotection and downstream coupling.
- High purity supports reproducible synthesis and analytical characterization.
- Liquid form simplifies handling and weighing for small-scale reactions.
- Suitable for assembling bifunctional degraders and other conjugates.
- Stable under frozen storage for extended shelf life.
Medchemexpress LLC C-C motif chemokine 6 (rat), recombinant, N-terminal His tag | >95.0% | 50UG
Recombinant rat C-C motif chemokine 6 (CCL6) with an N-terminal His tag, expressed in E. coli and provided as a lyophilized protein for immunology and cell-based assays. The product corresponds to residues G22-A115 of accession Q68FP3 and shows biological activity (ED50 15.84 ng/mL).
- N-terminal His-tagged recombinant rat chemokine.
- Amino acid range G22-A115 (accession Q68FP3).
- Expression system: E. coli; lyophilized formulation from 50 mM Tris-HCl, 300 mM NaCl, pH 7.4.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Endotoxin level <1 EU/μg (LAL method).
- Approximate molecular weight ~12 kDa.
- Stable when stored at -20°C; reconstituted stability 4°C for 1 week or -20°C longer with carrier protein.
C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 5g | 602865744](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000188316.jpg-250.jpg)
eMolecules 120205-50-7 | N-Boc-dolaproine | ChemScene | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 5g | 602865744
N-Boc-dolaproine | ChemScene | 120205-50-7 | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 5g | 602865744
Medchemexpress LLC Benzyl-PEG4-Boc | 2484091-04-3 | 368.46 | 250 MG
Benzyl-PEG4-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two different ligands connected by a linker, one for an E3 ubiquitin ligase and another for the target protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
eMolecules 98-80-6 | Phenylboronic acid | Key Organics/BIONET | MFCD00002103 | 121.930 | C6H7BO2 | 95.000 | OB(O)c1ccccc1 | 10mg | 564101484
Phenylboronic acid | Key Organics/BIONET | 98-80-6 | MFCD00002103 | 121.930 | C6H7BO2 | 95.000 | OB(O)c1ccccc1 | 10mg | 564101484
eMolecules 127828-22-2 | Amino-PEG2-NH-Boc | Ambeed | MFCD12031501 | 204.270 | C9H20N2O3 | 97.000 | CC(C)(C)OC(=O)NCCOCCN | 1g | 524997255
Amino-PEG2-NH-Boc | Ambeed | 127828-22-2 | MFCD12031501 | 204.270 | C9H20N2O3 | 97.000 | CC(C)(C)OC(=O)NCCOCCN | 1g | 524997255
Medchemexpress LLC N-desmethyl apalutamide | 99.7% | 463.41 g/mol | C20H13F4N5O2S | 1mg
N-Desmethyl apalutamide-d4 is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331) N-Desmethyl Apalutamide is an active metabolite of Apalutamide N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4 N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3]
Medchemexpress LLC Acid-PEG3-C2-Boc | 1807539-06-5 | ≥97.0% | 5 G
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker. It can be utilized in the synthesis of PROTACs for the degradation of EGFR and the inhibition of mTOR. PROTACs are composed of two distinct ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Degrades EGFR
- Inhibits mTOR
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins