Phenylcarbamic acid esters
Medchemexpress LLC N-Boc-4-hydroxy-L-proline methyl ester | 102195-79-9 | >=98.0% | 245.28 g·mol⁻1 | C11H19NO5 | 25 G
N-Boc-4-hydroxy-L-proline methyl ester is a Boc-protected hydroxyproline derivative supplied as a research-grade building block used in medicinal chemistry and linker synthesis for ADCs and PROTACs.
- Used as a non-cleavable ADC linker building block
- Suitable for PROTAC linker synthesis
- Boc-protected hydroxyproline methyl ester functional group enables selective transformations
- Provided in gram-scale quantities for synthesis and scale-up
Aobchem (4-Benzyl-2 6-dichlorophenyl)(methyl)sulfane | 95% | C14H12Cl2S | 500mg
(4-Benzyl-2 6-dichlorophenyl)(methyl)sulfane | 95% | C14H12Cl2S | 500mg
Medchemexpress LLC N-Boc-N-bis(PEG2-acid) | 2054339-01-2 | 99.9% | C19H35NO10 | 100 MG
N-Boc-N-bis(PEG2-acid) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other targeting a protein of interest. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation
- For research use only
Medchemexpress LLC N-hydroxyisonicotinamidine | 1594-57-6 | MFCD00125873 | 99.9% | 137.14 g·mol^-1 | C6H7N3O | 10 G
N-hydroxyisonicotinamidine is an amidoxime-based chemical intermediate and collector used in research-scale organic synthesis. It is employed in the preparation of substituted α-1,2,4-oxadiazole esters and related heterocycles. The compound has formula C6H7N3O and a molecular weight of 137.14, and is supplied as a high-purity reagent for laboratory use.
- Amidoxime functional group suitable for heterocycle construction.
- Documented application in synthesis of substituted α-1,2,4-oxadiazole esters.
- Provided as a high-purity reagent for research applications.
- Stable as a powder when stored under recommended conditions.
- Available in small pack sizes tailored for laboratory use.
Medchemexpress LLC Amino-PEG10-Boc | 1818294-42-6 | 99.7% | C27H55NO12 | 100 MG
Amino-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Available in 100 mg for purchase.
- CAS number: 1818294-42-6.
- Purity: 99.73%.
- Chemical formula: C27H55NO12.
- Molecular weight: 585.73.
- Appearance: Liquid (density: 1.074 g/cm3), colorless to light yellow.
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light).
Chem-Impex International, Inc. Boc-1,4-phenylenediamine | 71026-66-9 | MFCD00043022 | 25G
Boc-1,4-phenylenediamine, 71026-66-9, MFCD00043022, 25G
Medchemexpress LLC Tert-butyl N-(6-bromohexyl)carbamate | 142356-33-0 | MFCD06201019 | 98.0% | 280.20 g/mol | C11H22BrNO2 | 5 G
Boc-NH-C6-Br is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It provides a stable, non-cleavable connection between an antibody and a cytotoxic payload and is supplied for research use only.
- Non-cleavable linker for ADC synthesis.
- Purity 98.0%.
- Molecular formula C11H22BrNO2; molecular weight 280.20 g/mol.
- Appearance colorless to off-white; form solid-liquid mixture.
- Storage: pure form -20°C for 3 years or 4°C for 2 years; in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research use only; not for human or veterinary applications.
Medchemexpress LLC Bromo-PEG8-Boc | 1623792-00-6 | 99.86% | C23H45BrO10 | 500 MG
Bromo-PEG8-Boc is a PEG-based PROTAC linker essential for the synthesis of Proteolysis-Targeting Chimeras (PROTACs). PROTACs are designed to contain two distinct ligands, one for an E3 ubiquitin ligase and another for a target protein, connected by a linker. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system, enabling the selective degradation of specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Applicable in cancer research
- Supports targeted therapy
Medchemexpress LLC N,N'-Dinitrosopiperazine | 140-79-4 | 99.94% | 144.13 | 1 ML
N,N'-Dinitrosopiperazine (DNP) is identified as a carcinogen with specificity for nasopharyngeal epithelium. It facilitates nasopharyngeal carcinoma (NPC) metastasis by regulating various signaling pathways, notably through the phosphorylation of LYRIC at serine 568. This compound is offered as a high-purity solution for research applications.
- Carcinogen with specificity for nasopharyngeal epithelium
- Facilitates NPC metastasis
- Regulates multiple signaling pathways via protein phosphorylation
- Targets LYRIC at serine 568
- Supplied as a 10 mM solution in DMSO
- High purity of 99.94%
eMolecules 958454-25-6 | 3-(2,2-Difluoroethoxy)bromobenzene | Apollo Scientific | MFCD11036117 | 237.044 | C8H7BrF2O | 95.000 | FC(F)COc1cccc(Br)c1 | 1g | 562431154
3-(2,2-Difluoroethoxy)bromobenzene | Apollo Scientific | 958454-25-6 | MFCD11036117 | 237.044 | C8H7BrF2O | 95.000 | FC(F)COc1cccc(Br)c1 | 1g | 562431154