Phenylhydrazines
eMolecules 368-78-5 | 3-(Trifluoromethyl)phenylhydrazine | Combi-Blocks, Inc. | MFCD00025093 | 176.142 | C7H7F3N2 | 95.000 | NNc1cccc(c1)C(F)(F)F | 1g | 569297439
3-(Trifluoromethyl)phenylhydrazine | Combi-Blocks, Inc. | 368-78-5 | MFCD00025093 | 176.142 | C7H7F3N2 | 95.000 | NNc1cccc(c1)C(F)(F)F | 1g | 569297439
Medchemexpress LLC Fructosamine hydrochloride | 39002-30-7 | >97.0% | 215.63 g/mol | C6H14ClNO5 | 25 MG
Fructosamine hydrochloride is the hydrochloride salt of D-isoglucosamine supplied as a white to off-white solid for biochemical research. It is used as a reagent and metabolic intermediate in studies of protein glycation, cell membrane biology, and related biochemical processes. Handle per standard laboratory safety practices.
- CAS number: 39002-30-7.
- Molecular formula: C6H14ClNO5.
- Molecular weight: 215.63 g/mol.
- Purity: ≥97.0%.
- Appearance: white to off-white solid.
- Storage: store sealed at 4°C; stock solutions -80°C (6 months) or -20°C (1 month).
- Pack sizes: available in mg-scale packs including 25 mg.
Medchemexpress LLC Pexidartinib (hydrochloride) | 2040295-03-0 | 99.8% | 454.28 | 1 G
Pexidartinib (hydrochloride) | 2040295-03-0 | 99.8% | 454.28 | 1 G
Medchemexpress LLC Besifloxacin Hydrochloride | 405165-61-9 | 98.5% | 430.30 | 50 MG
Besifloxacin Hydrochloride is a fourth-generation fluoroquinolone antibiotic that functions as a DNA gyrase and topoisomerase IV inhibitor. It demonstrates broad-spectrum antibacterial activity against various Gram-negative and Gram-positive aerobic and anaerobic strains, while also exhibiting anti-inflammatory properties and reducing the incidence of drug resistance.
- Inhibits DNA gyrase and topoisomerase IV.
- Exhibits broad-spectrum antibacterial activity.
- Effective against Gram-negative and Gram-positive aerobic and anaerobic strains.
- Reduces the incidence of drug resistance.
- Possesses anti-inflammatory activity.
- Can be utilized in bacterial conjunctivitis research.
Medchemexpress LLC (+)-Niguldipine hydrochloride | 113145-69-0 | MFCD00873564 | 98.1% | 646.17 g/mol | C36H40ClN3O6 | 1 MG
(+)-Niguldipine hydrochloride is the S-enantiomer of niguldipine, a dihydropyridine calcium channel antagonist used in research to probe L-type calcium channel-mediated signaling and vasodilation mechanisms. It is supplied as an off-white to yellow solid with high purity for laboratory applications.
- High purity suitable for analytical and biological assays.
- S-enantiomer useful for enantiospecific pharmacology studies.
- Small vials appropriate for screening and mechanistic experiments.
- Off-white to yellow solid form simplifies handling and formulation.
- Storage recommendations provided for sealed samples and solvent solutions.
Medchemexpress LLC Ruboxistaurin hydrochloride | 169939-93-9 | MFCD00940226 | 99.9% | 505.01 g/mol | C28H29ClN4O3 | 1 MG
Ruboxistaurin hydrochloride is the hydrochloride salt of ruboxistaurin (LY333531), a selective ATP-competitive inhibitor of protein kinase C beta (PKCβ) supplied for research use in biochemical, cellular, and in vivo studies probing PKCβ-mediated signaling.
- Selective PKCβ inhibition with low-nanomolar potency.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO (25 mg/mL) with ultrasonic warming.
- Storage: sealed at 4°C; in solvent -20°C (1 month) or -80°C (6 months).
- Supplied in small research pack sizes such as 1 mg.
Medchemexpress LLC Procarbazine (Hydrochloride) | 366-70-1 | 99.7% | 257.76 | 500 MG
Procarbazine (Hydrochloride) is an orally active alkylating agent with anticancer activity. It is suitable for research applications, particularly in studies related to Hodgkin's disease.
- Orally active alkylating agent
- Demonstrates anticancer activity
- Suitable for Hodgkin's disease research
- High purity of 99.7%
- Provided as a solid
- Recommended storage for solid: 4°C, sealed, away from moisture
- Recommended storage for in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Itacnosertib hydrochloride | 2409543-84-4 | 99.4% | 505.01 | C26H29ClN8O | 5 MG
Itacnosertib hydrochloride is the hydrochloride salt of TP-0184, a small-molecule investigational inhibitor that potently targets ACVR1/ALK2 (reported IC50 ≈ 8 nM), shows activity against FLT3, and has markedly weaker activity versus JAK2 (reported IC50 ≈ 8,540 nM). It has demonstrated anti-leukemic activity in preclinical studies and is supplied for research use as a high-purity hydrochloride salt.
- Potent ACVR1/ALK2 inhibition (IC50 ≈ 8 nM).
- Activity against FLT3 with reported anti-leukemic effects.
- Markedly weaker JAK2 activity (IC50 ≈ 8,540 nM), indicating selectivity.
- Supplied as the hydrochloride salt for improved solubility.
- High reported purity (~99.4%) backed by certificate of analysis.
- Provided in small research pack sizes suitable for in vitro studies.
Medchemexpress LLC 2-Methyl-1,2,5,6-tetrahydro-3H-pyrrolo[3,2,1-ij]quinazolin-3-imine hydrochloride | C11H14ClN3 | 5 MG
JBSNF-000028 hydrochloride is an orally active, small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT) with IC50 values of 33 nM for human NNMT. It effectively reduces endogenous MNA levels in U2OS osteosarcoma cells with an EC50 of 2.5 μM. This compound has demonstrated significant anti-obesity and anti-diabetic activities in diet-induced obesity models.
- Inhibits NNMT activity with an EC50 of 2.5 μM in U2OS cells
- Shows no cytotoxicity against HepG2 cells at 10-100 μM
- Improves glucose and lipid handling in mice with diet-induced obesity
- Improves glucose tolerance in NNMT knockout mice with diet-induced obesity
- Used for studying metabolic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease
Medchemexpress LLC Valacyclovir (hydrochloride) | 124832-27-5 | 99.9% | 360.80 | 25 MG
Valacyclovir hydrochloride is an orally active antiviral agent effective against herpes simplex, herpes zoster, and herpes B. It acts as a proagent of Aciclovir, inhibiting HSV-1. Its uptake is concentration dependent and saturable, suggesting hPEPT1 dominates its intestinal transport in vitro. Clinical trials show its effectiveness in treating genital herpes and recurrences, with a 1 g daily dose being as effective as 2 g daily.
- Orally active antiviral agent
- Effective against herpes simplex, herpes zoster, and herpes B
- Inhibits HSV-1 with an IC50 of 2.9 μg/ml
- Proagent of Aciclovir
- Uptake is concentration dependent and saturable
- Effective for treating genital herpes and recurrences
- Daily dose of 1 g is as effective as 2 g daily
Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.9% | 236.74 | 50 MG
Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist with a Ki of 1.08 nM. It exhibits sedative and analgesic effects and can induce peripheral vasoconstriction by activating α2 adrenoceptors on blood vessels.
- Orally active α2-adrenoceptor agonist (Ki: 1.08 nM).
- Possesses sedative and analgesic effects.
- Causes peripheral vasoconstriction through α2 adrenoceptor activation.
- Inhibits aldosterone release from adrenocortical cell suspension in vitro.
- Activates a kicking response in Cyprids in vitro.
- Increases cellular cAMP production by activating β-like receptors in CHO cells in vitro.
- Induces sedation in cats in vivo.
- Shows sedative and analgesic effects in dogs in vivo.
- Protects against Diazinon-induced toxicosis in mice in vivo.
Medchemexpress LLC Valacyclovir (hydrochloride) | 124832-27-5 | 99.02% | 360.80 | 25 MG
Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent effective against herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 W (50=2.9 μg/ml) and is a prodrug of Aciclovir (HY-17422). This product is intended for research and analytical applications.
- Orally active antiviral agent
- Effective against herpes simplex, herpes zoster, and herpes B
- Inhibits HSV-1 W (50=2.9 μg/ml)
- Prodrug of aciclovir
- Intended for research and analytical applications
Medchemexpress LLC Idalopirdine hydrochloride | 467458-02-2 | 99.6% | C20H20ClF5N2O | 50 MG
Idalopirdine hydrochloride is a potent and selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM. It is primarily used in research studies related to Alzheimer's disease and schizophrenia. This product is for research use only.
- Potent and selective 5-HT6 receptor antagonist
- Ki value: 0.83 nM
- Supports studies in Alzheimer's disease
- Supports studies in schizophrenia
- Reduces food intake and body weight in over-eating rat models
- Increases gamma power during nPO electrical stimulation
- Enhances donepezil effects on cortical gamma oscillations
Medchemexpress LLC Phentolamine hydrochloride | 73-05-2 | 99.9% | 25 MG
Phentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent. It is intended for research use only.
- Orally active
- Acts as an α receptor-blocking agent
- For research use only
Medchemexpress LLC 2-bromo-4-methylphenol | 6627-55-0 | MFCD00002151 | 99.3% | 187.03 g/mol | C7H7BrO | 250 G
2-Bromo-4-methylphenol is an aromatic brominated phenol used as a biochemical reagent and organic intermediate for life-science research. It is provided with purity and handling information and is intended for laboratory research use only.
- High purity (≈99.3%) suitable for analytical and synthetic applications.
- Well-characterized: molecular formula C7H7BrO and molecular weight 187.03 g/mol.
- Soluble in DMSO; solubility data and suggested formulations provided for in vitro and in vivo use.
- Stable when stored frozen; datasheet specifies storage guidelines for pure material and solutions.
- Available in multiple pack sizes to support small-scale research and scale-up work.