Phenylhydrazines
Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.8% | 236.74 | 1 ML
Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist with sedative and analgesic effects. It can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. It is for research use only.
- Orally active α2-adrenoceptor agonist (Ki: 1.08 nM)
- Sedative and analgesic effects
- Causes peripheral vasoconstriction through activation of α2 adrenoceptors
- Inhibits aldosterone release from adrenocortical cell suspension in vitro
- Activates a kicking response in Cyprids in vitro
- Increases cellular cAMP production by activating β-like receptors in CHO cells in vitro
- Induces sedation in cats in vivo
- Shows sedative and analgesic effects in dogs in vivo
- Protects against Diazinon-induced toxicosis in mice in vivo
Medchemexpress LLC Pioglitazone hydrochloride | 112529-15-4 | MFCD00865768 | ≥98.0% | C19H21N3O3S·HCl | 25 MG
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC50s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. It can be used in diabetes research.
- Potent and selective PPARγ agonist.
- EC50s of 0.93 and 0.99 μM for human and mouse PPARγ.
- Suitable for diabetes research.
Medchemexpress LLC Pheniprazine hydrochloride | 66-05-7 | 98.7% | 186.68 g·mol⁻¹ | C9H15ClN2 | 50 MG
Pheniprazine hydrochloride is the hydrochloride salt of pheniprazine, an irreversible, nonselective monoamine oxidase (MAOI) inhibitor supplied for research use in biochemical and pharmacological studies of monoamine systems and depression.
- Irreversible, nonselective monoamine oxidase inhibitor.
- Useful research tool for studies of depression and monoaminergic signaling.
- Supplied as a white to off-white solid.
- Typical purity about 98.7%.
- Available in small research quantities, for example 50 mg.
- Store solid at 4°C, sealed and away from moisture; in solution store at -80°C for long-term storage.
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.1% | 343.38 | 5 MG
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. It demonstrates strong anticancer effects.
- Exhibits strong growth-inhibitory activity in cancer cell lines of both hematologic and solid tumor origin.
- Functions as a dihydroorotate dehydrogenase (DHODH) inhibitor.
- Applications:
- In vitro: has shown strong growth-inhibitory activity in various cancer cell lines.
- In vivo: treatment resulted in robust tumor growth inhibition in the OCILY19 DLBCL tumor xenograft model.
- Clinical trials: being investigated in a Phase 1 clinical trial (NCT03834584) for lymphoma, which started on May 24, 2019.
Medchemexpress LLC Raclopride-d5 hydrochloride | 1217623-85-2 | 99.8% | 352.27 | C15H16D5Cl3N2O3 | 1 MG
Raclopride-d5 hydrochloride is the deuterium-labeled (d5) isotopologue of raclopride supplied as the hydrochloride salt and intended for use as an analytical reference standard or stable-isotope internal standard for quantitative assays.
- Deuterated raclopride (d5) for use as an internal standard.
- Hydrochloride salt in solid form for stable handling.
- High purity (99.82%) suitable for analytical applications.
- Molecular weight 352.27 and formula C15H16D5Cl3N2O3.
- Available in small reference sizes (1 mg) for trace-level assays.
- Certificate of analysis and safety data sheet available for quality verification.