Phenylhydrazines
Medchemexpress LLC Itacnosertib hydrochloride | 2409543-84-4 | 99.4% | 505.01 | C26H29ClN8O | 5 MG
Itacnosertib hydrochloride is the hydrochloride salt of TP-0184, a small-molecule investigational inhibitor that potently targets ACVR1/ALK2 (reported IC50 ≈ 8 nM), shows activity against FLT3, and has markedly weaker activity versus JAK2 (reported IC50 ≈ 8,540 nM). It has demonstrated anti-leukemic activity in preclinical studies and is supplied for research use as a high-purity hydrochloride salt.
- Potent ACVR1/ALK2 inhibition (IC50 ≈ 8 nM).
- Activity against FLT3 with reported anti-leukemic effects.
- Markedly weaker JAK2 activity (IC50 ≈ 8,540 nM), indicating selectivity.
- Supplied as the hydrochloride salt for improved solubility.
- High reported purity (~99.4%) backed by certificate of analysis.
- Provided in small research pack sizes suitable for in vitro studies.
eMolecules Phenylhydrazine | Oakwood Chemicals | 100-63-0 | MFCD00007573 | 108.144 | C6H8N2 | 97.000 | NNc1ccccc1 | 50g | 480149105
Phenylhydrazine | Oakwood Chemicals | 100-63-0 | MFCD00007573 | 108.144 | C6H8N2 | 97.000 | NNc1ccccc1 | 50g | 480149105
eMolecules N-Methyltyramine hydrochloride | 13062-76-5 | MFCD01707290 | 1g
WuXi ChemSupply | N-Methyltyramine hydrochloride | 1g | 599167502 | LN01308479 | 95.000 | 13062-76-5 | MFCD01707290 | 187.670 | C9H14ClNO
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Medchemexpress LLC Hydroxylamine, O-methyl-, hydrochloride (1:1) | 593-56-6 | MFCD00012951 | 98.0% | 83.52 | CH6ClNO | 100g
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor Methoxyamine hydrochloride binds to 3 hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2]
Medchemexpress LLC Sonlicromanol (hydrochloride) | 2162149-24-6 | 99.9% | 10MM 1ML
Sonlicromanol (hydrochloride) | 2162149-24-6 | 99.9% | 10MM 1ML
eMolecules 2,6-Dimethylmorpholine hydrochloride | 80567-00-6 | MFCD28099212 | 25g
Ambeed | 2,6-Dimethylmorpholine hydrochloride | 25g | 600843443 | A576751 | | 80567-00-6 | MFCD28099212 | 151.630 | C6H14ClNO
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