Phenylhydrazines
Medchemexpress LLC Cdk4/6-in-15 | 00-00-0 | 99.3% | 442.56 g/mol | C21H27FN8S | 5 MG
CDK4/6-IN-15 is an orally active, selective inhibitor of cyclin-dependent kinases CDK4 and CDK6 used in cellular and biochemical research to probe cell-cycle regulation and anticancer activity. It arrests cells in G1, suppresses Rb phosphorylation, and has demonstrated antiproliferative and pro-apoptotic effects in multiple cell lines.
- selective inhibitor of CDK4 and CDK6 with potent activity
- arrests the cell cycle at G1 and reduces Rb phosphorylation
- demonstrated antiproliferative and pro-apoptotic effects in cell assays
- soluble in DMSO with stock preparation guidance for common concentrations
- stable when protected from light; storage recommendations provided
eMolecules 6971-45-5 | (2-METHOXYPHENYL)HYDRAZINE HYDROCHLORIDE | AstaTech | MFCD00035456 | 174.630 | C7H11ClN2O | 95.000 | Cl.COc1ccccc1NN | 25g | 451911236
(2-METHOXYPHENYL)HYDRAZINE HYDROCHLORIDE | AstaTech | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 95.000 | Cl.COc1ccccc1NN | 25g | 451911236
Medchemexpress LLC Diclofensine hydrochloride | 34041-84-4 | 99.8% | 358.69 | 5 MG
Diclofensine (hydrochloride), also known as Ro 8-4650 hydrochloride, is an orally active neuronal monoamine uptake inhibitor. It effectively blocks the reuptake of dopamine, noradrenaline, and serotonin in rat brain synaptosomes, with IC50 values of 0.74, 2.3, and 3.7 nM, respectively. This compound has been shown to potentiate norepinephrine-induced hypertension while attenuating Tyramine-induced hypertension. It is recognized for producing psychostimulant and mood-elevating effects without the common issues of sudden disappearance or withdrawal reactions, making it a valuable tool in the research of moderate to severe depression.
- Blocks the uptake of dopamine, noradrenaline, and serotonin
- Potentiates norepinephrine-induced hypertension
- Attenuates Tyramine-induced hypertension
- Produces psychostimulant and mood-elevating effects
- Used in the research of moderate to severe depression