Phenylhydrazines
eMolecules 4751-99-9 | o-Tolylbiguanide hydrochloride | Oakwood Chemical | MFCD00050547 | 227.700 | C9H14ClN5 | 98.000 | Cl.Cc1ccccc1NC(=N)NC(N)=N | 1g | 537707739
o-Tolylbiguanide hydrochloride | Oakwood Chemical | 4751-99-9 | MFCD00050547 | 227.700 | C9H14ClN5 | 98.000 | Cl.Cc1ccccc1NC(=N)NC(N)=N | 1g | 537707739
Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 454.28 g/mol | C20H16Cl2F3N5 | 10 MG
Pexidartinib hydrochloride is a research-grade small-molecule tyrosine kinase inhibitor that selectively targets colony stimulating factor 1 receptor (CSF1R) and c-Kit. It is used in preclinical studies to investigate signaling pathways, tumor biology, and kinase-driven cellular responses. The compound is provided as the hydrochloride salt and is intended for laboratory research use only.
- Selective CSF1R and c-Kit inhibitor with low-nanomolar potency.
- Provided as the hydrochloride salt for stability and handling.
- Suitable for in vitro and in vivo preclinical research; not for human use.
- Characterized by CAS number 2040295-03-0 for unambiguous identification.
- Molecular formula C20H16Cl2F3N5; molecular weight 454.28 g/mol.
- Available in small pack sizes appropriate for laboratory experiments, including 10 mg.
eMolecules 6971-45-5 | 2-Methoxyphenylhydrazine Hydrochloride | Ambeed | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 5g | 552742604
2-Methoxyphenylhydrazine Hydrochloride | Ambeed | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 96.000 | Cl.COc1ccccc1NN | 5g | 552742604
Medchemexpress LLC Clomipramine (hydrochloride) | 17321-77-6 | 99.6% | 1 ML
Clomipramine hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. This tricyclic antidepressant is used in research for depression and obsessive compulsive disorder (OCD).
- Potent 5-HT reuptake blocker.
- Tricyclic antidepressant for depression and OCD research.
- Inhibits reuptake of both noradrenaline and 5-HT.
- Interferes with autophagic flux and compromises tumorigenic cell viability.
- Reduces autophagy in neuronal primary cultures.
- Elicits hyperglycemia in mice by blocking 5-HT2B and/or 5-HT2C receptors.
- Reduces immobility in the forced swimming test in mice.
- Inhibits marble burying behavior in mice.
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eMolecules 636-99-7 | 4-Nitrophenylhydrazine hydrochloride | Oakwood Chemical | MFCD00040592 | 189.600 | C6H8ClN3O2 | 90.000 | Cl.NNc1ccc(cc1)[N+]([O-])=O | 1g | 537681554
4-Nitrophenylhydrazine hydrochloride | Oakwood Chemical | 636-99-7 | MFCD00040592 | 189.600 | C6H8ClN3O2 | 90.000 | Cl.NNc1ccc(cc1)[N+]([O-])=O | 1g | 537681554
Medchemexpress LLC Lomefloxacin (hydrochloride) | 98079-52-8 | 100.0% | 500 MG
Lomefloxacin hydrochloride is an orally active difluoroquinolone antibiotic. It functions by preventing DNA supercoiling and replication through the inhibition of bacterial topoisomerase II. This compound is known to induce ROS production and apoptosis, demonstrating broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. It also exhibits anticancer effects, particularly against melanoma.
- Orally active difluoroquinolone antibiotic
- Inhibits bacterial topoisomerase II, preventing DNA supercoiling and replication
- Induces ROS production and apoptosis
- Provides broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria
- Exhibits anticancer effects against melanoma
- Useful for studying systemic bacterial infections, skin, and melanoma
- Rapidly reduces viable cell counts of common bacteria
Medchemexpress LLC Jbsnf-000028 hydrochloride | 3026599-90-3 | 95.6% | 223.7 | C11H14ClN3 | 10 MG
JBSNF-000028 hydrochloride is the hydrochloride salt of a tricyclic small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor supplied as a solid research reagent for preclinical in vitro and in vivo studies of metabolic regulation and NNMT-associated pathways.
- Orally active NNMT inhibitor for metabolic research.
- Hydrochloride salt form to aid solubility and handling.
- Supplied as an off-white to light yellow solid suitable for experimental use.
- High purity (95.6%) appropriate for research applications.
- Available in small milligram pack sizes for preclinical studies.
- Store sealed, away from moisture and light for stability.
Medchemexpress LLC Itacnosertib hydrochloride | 2409543-84-4 | 99.43% | 505.01 | 10 MG
Itacnosertib hydrochloride (TP-0184 hydrochloride) is an inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM), and JAK2 (IC50=8540 nM). It exhibits anti-leukemic activity. It also:
- Inhibits FLT3, ACVR1 (ALK2), and JAK2.
- Exhibits anti-leukemic activity.
- Arrests the cell cycle of MOLM-13, MOLM-14, and MV4-11 at G1/G0 phase.
- Inhibits the proliferation of acute myeloid leukemia (AML) cells (IC50s for MOLM-13, MOLM-14 and MV4-11 are 6.4, 1.2 and 1.3 nM, respectively).
- Inhibits activation of FLT3 and ACVR1 downstream signaling pathways.
- Inhibits serine biosynthesis and amino acid transport pathways.
- Exhibits antitumor activity against MOLM-13 in mouse models.