Phenylhydrazines
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Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.8% | 236.74 | 5 MG
Medetomidine hydrochloride from MedChemExpress is provided for laboratory chemical applications and substance manufacturing. This product is a white to off-white solid.
- Suitable for laboratory chemicals and substance manufacturing
- White to off-white solid appearance
- Store at 4°C, sealed and away from moisture
- Purity of 99.8% confirmed by LCMS
- For research use only; not validated for medical applications
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Medchemexpress LLC Pyridostatin hydrochloride | 1781882-65-2 | C31H37Cl5N8O5 | 100 MG
Pyridostatin hydrochloride is a potent G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s within cells. It effectively promotes growth arrest in various human cancer cells by inducing replication- and transcription-dependent DNA damage. This highly selective molecule also specifically targets the proto-oncogene Src, leading to a reduction in SRC protein levels and SRC-dependent cellular motility, particularly in human breast cancer cells.
- Stabilizes G-quadruplex DNA (Kd=490 nM)
- Targets DNA and RNA G4s in cellular environments
- Promotes growth arrest in human cancer cells
- Induces replication- and transcription-dependent DNA damage
- Reduces SRC protein levels and cellular motility in breast cancer cells
- Highly selective G-quadruplex DNA-binding small molecule
- Induces cell cycle arrest in over 60 cancer cell lines
- Downregulates the BRCA1 protein transcriptionally
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