Phenylhydrazines
Medchemexpress LLC Aminoacetone hydrochloride | 7737-17-9 | 109.55 | 10 G
Aminoacetone hydrochloride is the simplest monopeptide, serving as an intermediate in the metabolism of threonine and glycine. This compound is also an endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO) and can be used for the determination of SSAO activity.
- Endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO)
- Can be utilized for determining SSAO activity
- Appearance: Light yellow to yellow solid
- Molecular formula: C3H8ClNO
- Soluble in DMSO: 200 mg/mL
Medchemexpress LLC (S)-Remoxipride hydrochloride | 73220-03-8 | 99.9% | 407.8 g·mol⁻¹ | C16H23BrN2O3·HCl | 50 MG
(S)-Remoxipride hydrochloride is the S-enantiomer of remoxipride, supplied as the hydrochloride salt for research use. It acts as a selective dopamine D2 receptor antagonist and is provided at high purity for in vitro and in vivo pharmacology studies.
- S-enantiomer with selective dopamine D2 receptor antagonist activity.
- Provided as the hydrochloride salt, white to off-white solid.
- High purity suitable for research applications.
- Commonly used in receptor binding and pharmacological assays.
- Available in small research quantities (e.g., 50 mg).
Medchemexpress LLC Almonertinib hydrochloride | 2134096-03-8 | 98.9% | 562.11 | 100 MG
Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows significant inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively) and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer.
- Orally available
- Irreversible
- Third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Significant inhibitory activity against T790M, T790M/L858R, and T790M/Del19
- Effective against other EGFR sensitive mutations including G719X, del19, L858R, and L861Q