Phenylhydrazines
Medchemexpress LLC 2,6-Pyridinedicarboxamide, 4-(2-aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-, hydrochloride (1:5) | 1781882-65-2 | C31H37Cl5N8O5 | 50 MG
Pyridostatin hydrochloride is a G-quadruplex DNA stabilizing agent that targets DNA and RNA G4s in cells. It promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. This compound targets the proto-oncogene Src, reducing SRC protein levels and SRC-dependent cellular motility in human breast cancer cells. It is suitable for research use only.
- Selective G-quadruplex DNA-binding small molecule
- Induces cell cycle arrest in over 60 different cancer cell lines
- Causes neurite retraction and synaptic loss
- Downregulates BRCA1 protein at the transcriptional level
Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 99.8% | 454.28 | 500 MG
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor. It induces cell apoptosis and exhibits anti-cancer activity, making it a valuable tool for cancer research.
- Potent, orally active, selective, and ATP-competitive inhibitor
- Targets CSF1R (M-CSFR) with an IC50 of 20 nM and c-Kit with an IC50 of 10 nM
- Exhibits 10- to 100-fold selectivity for these targets over other related kinases
- Induces cell apoptosis and shows anti-cancer activity
- Can deplete microglia cells in mice and reduces tissue macrophage levels
- For research use only
Medchemexpress LLC Valacyclovir hydrochloride (Standard) | 124832-27-5 | 99.0% | 360.80 | 5 MG
Valacyclovir (hydrochloride) (Standard) is the analytical standard of Valacyclovir (hydrochloride). This product is intended for research and analytical applications. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 W (50=2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422).
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Accela Chembio Inc 4-(trifluoromethoxy)phenylhydrazine Hydrochloride | 25g | 133115-72-7 | MFCD00053033 | 97+% | Shelf Life: 1260 Days | N2
4-(trifluoromethoxy)phenylhydrazine Hydrochloride | 25g | 133115-72-7 | MFCD00053033 | 97+% | Shelf Life: 1260 Days | N2
eMolecules 368-78-5 | 3-(Trifluoromethyl)phenylhydrazine | Combi-Blocks, Inc. | MFCD00025093 | 176.142 | C7H7F3N2 | 95.000 | NNc1cccc(c1)C(F)(F)F | 1g | 569297439
3-(Trifluoromethyl)phenylhydrazine | Combi-Blocks, Inc. | 368-78-5 | MFCD00025093 | 176.142 | C7H7F3N2 | 95.000 | NNc1cccc(c1)C(F)(F)F | 1g | 569297439
Accela Chembio Inc 3-fluorophenylhydrazine Hydrochloride | 25g | 2924-16-5 | MFCD00012934 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
3-fluorophenylhydrazine Hydrochloride | 25g | 2924-16-5 | MFCD00012934 | 97+% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/+4
Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | MFCD00069234 | 99.6% | 25 MG
Clomipramine hydrochloride is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM. It acts as a tricyclic antidepressant, primarily researched for its effects on depression and obsessive compulsive disorder (OCD). It significantly inhibits both noradrenaline and 5-HT reuptake, with a stronger selectivity for 5-HT.
- Potent 5-HT reuptake blocker with an IC50 value of 1.5 nM
- Used in research for depression and obsessive compulsive disorder (OCD)
- Inhibits noradrenaline and 5-HT reuptake, stronger for 5-HT
- Interferes with autophagic flux, impacting tumorigenic cell viability
- Reduces autophagy in neuronal primary cultures
- Can induce hyperglycemia in mice
eMolecules 6971-45-5 | 2-Methoxyphenylhydrazine hydrochloride | Combi-Blocks | MFCD00035456 | 174.630 | C7H11ClN2O | 97.000 | Cl.COc1ccccc1NN | 25g | 205388129
2-Methoxyphenylhydrazine hydrochloride | Combi-Blocks | 6971-45-5 | MFCD00035456 | 174.630 | C7H11ClN2O | 97.000 | Cl.COc1ccccc1NN | 25g | 205388129
Medchemexpress LLC 2-Bromo-4-methylphenol | 6627-55-0 | MFCD00002151 | 99.3% | 187.03 g/mol | C7H7BrO | 50 G
2-Bromo-4-methylphenol is a brominated phenol compound used as a biochemical reagent and intermediate in organic synthesis. It is employed in research applications and chemical synthesis where a functionalized aromatic building block is required. The material is supplied as a high-purity solid with supporting technical and safety documentation for laboratory use.
- High purity suitable for research applications.
- Useful intermediate for organic synthesis.
- Acts as a building block for functionalized aromatic compounds.
- Supplied as a stable solid for storage and handling.
- Includes technical data sheet and safety data sheet for safe use.