Sulfanylbenzoic acids and derivatives
Medchemexpress LLC TAS-119 | 1453099-83-6 | 98.0% | 506.36 | 25 MG
TAS-119 is a potent, selective, and orally active Aurora A inhibitor. It exhibits an IC50 of 1.0 nM for Aurora A and 95 nM for Aurora B. This compound has demonstrated potent antitumor activities, enhancing the antiproliferative effect of Paclitaxel in various human cancer cell lines, including drug-resistant ones.
- Potent, selective, and orally active Aurora A inhibitor
- IC50 of 1.0 nM for Aurora A
- High selectivity over Aurora B (IC50 of 95 nM)
- Demonstrates potent antitumor activities
- Enhances antiproliferative effect of Paclitaxel
- Induces mitotic accumulation in tumor cells
- For research use only
Selleck Chemical LLC Anti-mouse Ter-119-InVivo-5MG
Anti-mouse Ter-119-InVivo reacts with mouse Ter-119 a 52 kDa glycophorin A-associated protein that is expressed by erythroid cells from the early proerythroblast stage to mature erythrocytes Anti-mouse Ter-119-InVivo is commonly used for identifying erythrocytes and cells in the erythroid lineage
Medchemexpress LLC Synstatin (92-119) | 1259384-47-8 | 99.4% | 3032.27 | 5 MG
Synstatin (92-119) is an inhibitor of αvβ3/αvβ5 integrins and IGF1R, exhibiting anti-angiogenic, anti-proliferative, antioxidant, and anti-tumor activities. It competitively blocks the capture of αvβ3/αvβ5 integrins and IGF1R by syndecan-1, disrupting the formation of the syndecan-1: integrin: IGF1R ternary complex. It also inhibits integrin activation, talin-mediated signaling, and VEGF-induced angiogenesis, making it suitable for cancer and hepatocellular carcinoma research.
- Directly inhibits assembly of Sdc1:αvβ3 integrin:IGF1R ternary complex
- Binds to αvβ3 integrin, αvβ5 integrin, and IGF1R on activated vascular endothelial cells
- Inhibits αvβ3-dependent adhesion and migration of tumor cells
- Inhibits VEGF- and αvβ3-dependent angiogenesis
- Reduces hepatocellular carcinoma progression in thioacetamide-induced rats
Medchemexpress LLC bFGF (119-126) | 152051-61-1 | 99.9% | 993.16 | 5 MG
bFGF (119-126) | 152051-61-1 | 99.9% | 993.16 | 5 MG
Medchemexpress LLC Anti-Mouse Ter-119 A 1mg | 1mg
Anti-Mouse Ter-119 Antibody (TER-119) is an anti-mouse Ter-119 IgG2b monoclonal antibody Anti-Mouse Ter-119 Antibody (TER-119) can increase platelet count Anti-Mouse Ter-119 Antibody (TER-119) can remove red blood cells and their precursor cells to isolate and enrich natural killer (NK) cells Anti-Mouse Ter-119 Antibody (TER-119) can be used for research on immune thrombocytopenia Anti-Mouse Ter-119 Antibody (TER-119) can be used to construct a model of immune thrombocytopenic purpura combined with CD41 mAb[1][2][3]
eMolecules 33441-56-4 | Ethyl thiosalicylate | Oakwood Chemical | MFCD24715924 | 182.240 | C9H10O2S | 0.000 | CCOC(=S)c1ccccc1O | 1g | 537705278
Ethyl thiosalicylate | Oakwood Chemical | 33441-56-4 | MFCD24715924 | 182.240 | C9H10O2S | 0.000 | CCOC(=S)c1ccccc1O | 1g | 537705278
Medchemexpress LLC TAS-119 | 1453099-83-6 | 98.0% | 506.36 | 1 ML
TAS-119 is a potent, selective, and orally active Aurora A inhibitor. It demonstrates high selectivity for Aurora A over other protein kinases and exhibits potent antitumor activities.
- Potent and selective Aurora A inhibitor with an IC50 of 1.0 nM.
- Shows high selectivity for Aurora A over Aurora B (IC50 of 95 nM).
- Enhances the antiproliferative effect of paclitaxel in various human cancer cell lines, including paclitaxel-resistant cells.
- Dose-dependently enhances cell growth inhibition by taxanes.
- Induces mitotic accumulation predominantly in tumor cells.
eMolecules 601514-19-6 | TWS 119 | Axon Medchem | MFCD09037535 | 318.336 | C18H14N4O2 | 99.000 | Nc1cccc(c1)-c1cc2c(Oc3cccc(O)c3)ncnc2[nH]1 | 5mg | 248226757
TWS 119 | Axon Medchem | 601514-19-6 | MFCD09037535 | 318.336 | C18H14N4O2 | 99.000 | Nc1cccc(c1)-c1cc2c(Oc3cccc(O)c3)ncnc2[nH]1 | 5mg | 248226757
eMolecules 121-57-3 | Sulfanilic acid | Combi-Blocks | MFCD00007886 | 173.190 | C6H7NO3S | 98.000 | Nc1ccc(cc1)S(O)(=O)=O | 1kg | 335344579
Sulfanilic acid | Combi-Blocks | 121-57-3 | MFCD00007886 | 173.190 | C6H7NO3S | 98.000 | Nc1ccc(cc1)S(O)(=O)=O | 1kg | 335344579
eMolecules 121-57-3 | Sulfanilic acid | Combi-Blocks | MFCD00007886 | 173.190 | C6H7NO3S | 98.000 | Nc1ccc(cc1)S(O)(=O)=O | 500g | 335344578
Sulfanilic acid | Combi-Blocks | 121-57-3 | MFCD00007886 | 173.190 | C6H7NO3S | 98.000 | Nc1ccc(cc1)S(O)(=O)=O | 500g | 335344578
eMolecules 4274-39-9 | 3-Amino-4-mercaptobenzoic acid hydrochloride | Advanced ChemBlocks - In Stock205.660 | C7H8ClNO2S | 95.000 | Cl.Nc1cc(ccc1S)C(O)=O | 5g | 457897169
3-Amino-4-mercaptobenzoic acid hydrochloride | Advanced ChemBlocks - In Stock | 4274-39-9205.660 | C7H8ClNO2S | 95.000 | Cl.Nc1cc(ccc1S)C(O)=O | 5g | 457897169
eMolecules 243977-23-3 | AstaTech | 4-TRIFLUOROMETHYLTHIO-PHENYLACETIC ACID | 1g | 489816772 | 22282 | 98 | MFCD00236351 | 236.21 | C9H7F3O2S
Ambeed | 26-Dichloro-3-nitrobenzaldehyde | 5g | 598443582 | A294623 | 5866-97-7 | MFCD00090332 | 220.010 | C7H3Cl2NO3
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eMolecules 121-57-3 | Sulfanilic acid | AA Blocks LLC | MFCD00007886 | 173.190 | C6H7NO3S | 0.000 | Nc1ccc(cc1)S(O)(=O)=O | 10g | 460596994
Sulfanilic acid | AA Blocks LLC | 121-57-3 | MFCD00007886 | 173.190 | C6H7NO3S | 0.000 | Nc1ccc(cc1)S(O)(=O)=O | 10g | 460596994
Medchemexpress LLC OP-1074 | 1443752-76-8 | 99.8% | 457.56 | 5 MG
OP-1074 is a pure anti-estrogen drug, functioning as a selective ER degrader (PA-SERD). It exhibits specific anti-estrogenic activity against ERα and ERβ.
- Inhibits 17β-estradiol (E2)-stimulated transcription with IC50 values of 1.6 nM for ERα and 3.2 nM for ERβ.
- Inhibits the proliferation of MCF-7 and CAMA-1 cells with IC50 values of 6.3 nM and 9.2 nM, respectively, after 24 hours.
- Destabilizes ERα protein expression in MCF-7 and CAMA-1 cells at 100 nM for 24 hours.