Sulfanylbenzoic acids and derivatives
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Medchemexpress LLC TAS-119 | 1453099-83-6 | 98.0% | 506.36 | 1 ML
TAS-119 is a potent, selective, and orally active Aurora A inhibitor. It demonstrates high selectivity for Aurora A over other protein kinases and exhibits potent antitumor activities.
- Potent and selective Aurora A inhibitor with an IC50 of 1.0 nM.
- Shows high selectivity for Aurora A over Aurora B (IC50 of 95 nM).
- Enhances the antiproliferative effect of paclitaxel in various human cancer cell lines, including paclitaxel-resistant cells.
- Dose-dependently enhances cell growth inhibition by taxanes.
- Induces mitotic accumulation predominantly in tumor cells.
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eMolecules 4-Bromo-6-(pentafluorothio)-1H-benzimidazole | 1432075-84-7 | MFCD24369706 | 1g
Apollo Scientific | 4-Bromo-6-(pentafluorothio)-1H-benzimidazole | 1g | 562428575 | PC51190 | 95.000 | 1432075-84-7 | MFCD24369706 | 323.080 | C7H4BrF5N2S
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