Cresols
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 25mg
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
Medchemexpress LLC Phospho-NF-KB p105/p50(Ser337) Antibody | 50 UL
Phospho-NF-KB p105/p50(Ser337) Antibody is a rabbit-derived, non-conjugated IgG polyclonal antibody specifically targeting Phospho-NF-KB p105/p50(Ser337). This affinity-purified antibody is intended for research use only. NF-kappa-B is a crucial transcription factor involved in inflammation, immunity, cell growth, and other essential biological processes across various cell types.
- Host: Rabbit
- Clonality: Polyclonal
- Reactivity: Human, mouse (predicted: rat, pig, cow)
- Applications: WB, IHC-P, IHC-F, FC, ICC/IF, ELISA
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Modification: Phosphorylated
- Isotype: IgG
- Formulation: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300, 50% Glycerol
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Shipping: With blue ice
- Purity: Affinity purified
Medchemexpress LLC 4-hydroxybenzaldehyde | 123-08-0 | MFCD00006939 | 100.0% | 122.12 g/mol | C7H6O2 | 1kg
p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma with antagonistic effect on GABAA receptor of the 1 2 2S subtype at high concentrations
TARGETMOL CHEMICALS INC BC-1471 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT LRR and PYD domains-containing protein 7) [1]. purity: 98%
Medchemexpress LLC β-cyclodextrin, 6A-(4-methylbenzenesulfonate) | 67217-55-4 | MFCD05864975 | 95.0% | 1289.17 g/mol | C49H76O37S | 1 G
Mono-(6-p-toluenesulfonyl)-β-cyclodextrin is a tosylated β-cyclodextrin derivative supplied as a purified powder. It is used as a building block for selective derivatization of cyclodextrins, for host-guest and supramolecular chemistry studies, and as an intermediate in organic synthesis where defined substitution at the 6-position enables controlled functionalization.
- Tosylated at the 6-position for selective substitution.
- Useful intermediate for synthesis and derivatization of cyclodextrins.
- Supports host-guest and supramolecular chemistry studies.
- Supplied as a powder with specified purity and storage instructions.
- Compatible with common organic solvents for further reactions.
Medchemexpress LLC o,p'-DDE (2,4'-DDE) | 3424-82-6 | 98.0% | 1 MG
o,p'-DDE (2,4'-DDE) is an organochlorine pesticide metabolite and degradation product of DDT used as an analytical reference in environmental and toxicology research. It is a persistent organic pollutant with documented endocrine-disrupting activity; handle and dispose according to institutional and regulatory safety guidance.
- Analytical reference standard for environmental and toxicology studies.
- Chemical formula C14H8Cl4; molecular weight 318.03 g/mol.
- Available in milligram pack sizes suitable for trace-level analyses.
- Useful for method development, calibration, and toxicological assays.
- Persistent organic pollutant; requires appropriate handling and disposal.
Medchemexpress LLC Hyaluronan-binding peptide, biotin labeled TFA | 2012.25 (free base) | 5 MG
Hyaluronan-binding peptide, biotin labeled TFA is a biologically active peptide. This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan found in the extracellular matrix and on cell surfaces. HA plays roles in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
- Biologically active peptide
- Biotinylated through a C-terminal GGGSK linker
- Blocks HA binding to CD44 receptors
- Inhibits T cell proliferation
Medchemexpress LLC (E)-p-Coumaramide | 194940-15-3 | 163.17 | 5 MG
(E)-p-Coumaramide is an α-Glucosidase inhibitor that can be isolated from Welsh onion. It is for research use only and not sold to patients.
- Alpha-glucosidase inhibitor
- Isolated from Welsh onion
- Target is glycosidase
- Pathway is metabolic enzyme/protease
- Purity of 95.0%
- Appearance as a solid
- Color is light yellow to yellow
Medchemexpress LLC R-1 Methanandamide Phosphate | 649569-33-5 | 98.0% | 1 ML
R-1 Methanandamide Phosphate is a water-soluble prodrug analog of arachidonylethanolamide (AEA), an endogenous cannabinoid compound. It is intended for research use only and not for patient use.
- Water-soluble prodrug analog of arachidonylethanolamide (AEA)
- Endogenous cannabinoid compound
- Appears as a viscous liquid
- Yellow to brown color
- For research use only
- Store at -20°C, protected from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Cyclophilin F/PPIF P 50ug
Cyclophilin F/PPIF protein is a peptidyl prolyl cis-trans isomerase (PPIase) that catalyzes the isomerization of proline imide peptide bonds and may contribute to protein folding It critically regulates the mitochondrial permeability transition pore (mPTP) affecting cell apoptosis or necrosis Cyclophilin F/PPIF Protein Human (HEK293 His) is the recombinant human-derived Cyclophilin F/PPIF protein expressed by HEK293 with C-6 His labeled tag