Cresols
BIOHIPPO h/m P53-sh-GFP-Puro
h/m P53-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
eMolecules 14786-82-4 | 4-Methoxy-3-methylphenol | MFCD09836708 | 1g
Medchem Express | 6H05 (TFA) | 5mg | 446261186 | HY-12408A | 2061344-88-3 | MFCD28167830 | 590.130 | C22H31ClF3N3O4S3
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eMolecules Building Block Tool<|a>
eMolecules 128-37-0 | Butylated hydroxytoluene | Target Molecule | MFCD00011644 | 220.356 | C15H24O | 0.000 | Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C | 100mg | 448758075
Butylated hydroxytoluene | Target Molecule | 128-37-0 | MFCD00011644 | 220.356 | C15H24O | 0.000 | Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C | 100mg | 448758075
Medchemexpress LLC m-Anisaldehyde (3-methoxybenzaldehyde) | 591-31-1 | 136.15 | 50 G
m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite appearing as a colorless to light yellow liquid with a density of 1.117 g/cm³. Its chemical formula is C8H8O2, and it is classified under Ketones, Aldehydes, and Acids, primarily sourced from plants.
- Endogenous metabolite associated with thyroid autoimmunity during early pregnancy
- Colorless to light yellow liquid
- Density: 1.117 g/cm³
- Chemical formula: C8H8O2
- Classified under ketones, aldehydes, and acids
- Primarily sourced from plants
- Recommended storage at 4°C under nitrogen
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC NH-bis(m-PEG8) | 2055013-64-2 | C34H71NO16 | 100 MG
NH-bis(m-PEG8) is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds designed to induce the degradation of target proteins by leveraging the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker for synthesis
- Enables synthesis of PROTACs
- Facilitates degradation of target proteins
- Utilizes the ubiquitin-proteasome system
eMolecules 149105-26-0 | Ambeed | Isobutyl 5-(25-dimethylphenoxy)-22-dimethylpentanoate | 5g | 779704306 | A748966 | MFCD08704557 | 306.446 | C19H30O3
Medchem Express | D-Ribose 5-phosphate (disodium dihydrate) | 5mg | 592903634 | HY-W009371C | 207671-46-3 | MFCD00149349 | 310.102 | C5H13Na2O10P
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eMolecules 1613373-40-2 | 1-(4-bromo-3,5-dimethylphenyl)-5,5-dimethylimidazolidine-2,4-dione | Advanced ChemBlocks | MFCD30803364 | 311.179 | C13H15BrN2O2 | 95.000 | Cc1cc(cc(C)c1Br)N1C(=O)NC(=O)C1(C)C | 1g | 784393395
1-(4-bromo-3,5-dimethylphenyl)-5,5-dimethylimidazolidine-2,4-dione | Advanced ChemBlocks | 1613373-40-2 | MFCD30803364 | 311.179 | C13H15BrN2O2 | 95.000 | Cc1cc(cc(C)c1Br)N1C(=O)NC(=O)C1(C)C | 1g | 784393395
eMolecules 77249-34-4 | 4-Fluoro-2,3-dimethylphenol | Ambeed | MFCD00153130 | 140.157 | C8H9FO | 95.000 | Cc1c(C)c(F)ccc1O | 250mg | 600842891
4-Fluoro-2,3-dimethylphenol | Ambeed | 77249-34-4 | MFCD00153130 | 140.157 | C8H9FO | 95.000 | Cc1c(C)c(F)ccc1O | 250mg | 600842891
Apexbio Technology LLC EZ Cap Mouse RLI mRNA (m1Ψ) 100ug (1mg/mL)
Mouse RLI mRNA encodes a fusion protein composed of interleukin-15 (IL-15) fused to the sushi domain of its receptor IL-15R representing an innovative immunotherapeutic agent As a crucial cytokine IL-15 stimulates proliferation of natural killer (NK) cells and T cells thus enhancing immune responses against tumor cells and viruses The IL-15/IL-15R -sushi fusion protein shows promise in cancer immunotherapy by enhancing immune cell function and promoting clearance of tumor cells EZ Cap Mouse RLI mRNA (m1 )is supplied at 1 mg/mL expresses mouse-derived RLI fusion protein It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cambridge Isotope Laboratories 4-Chloro-3-methylphenol (ring-2 6-D2 98%) 0 01 g
4-Chloro-3-methylphenol (ring-2 6-D2 98%) 0 01 g
Medchemexpress LLC M-PEG-mal (MW 30000) | 98.0% | 500 MG
M-PEG-mal (MW 30000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands joined by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Enables synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system
- Degrades target proteins selectively
- Features two ligands connected by a linker
- One ligand for E3 ubiquitin ligase, one for target protein
Medchemexpress LLC Frizzled-10/CD350 M 10ug
Frizzled-10/CD350 protein is a receptor for Wnt proteins that functions in the canonical Wnt/ -catenin pathway activating disheveled proteins inhibiting GSK-3 kinase and triggering Wnt target gene activation Secondary signaling pathways involve PKC and calcium flux Frizzled-10/CD350 Protein Mouse (HEK293 His) is the recombinant mouse-derived Frizzled-10/CD350 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Azoreductase/NQO1 M 5ug
Recombinant mouse Azoreductase/NQO1 enzyme expressed in Pichia pastoris with an N-terminal 6xHis tag, supplied lyophilized and formulated to preserve activity. The protein catalyzes two-electron reduction of quinones using NADH or NADPH and is suitable for biochemical assays, enzymology, and cellular redox studies.
- Recombinant mouse enzyme expressed in Pichia pastoris.
- N-terminal 6xHis tag for purification and detection.
- Lyophilized formulation for extended shelf life and transport.
- Purity greater than 90% by reducing SDS-PAGE for consistent performance.
- Suitable for biochemical assays, kinetic studies, and redox research.
- Stable when stored frozen; follow reconstitution and storage guidance.
Medchemexpress LLC (2-chlorophenyl)(phenyl)methanone | 5162-03-8 | MFCD00000558 | 98.8% | 216.66 g/mol | C13H9ClO | 25 G
(2-Chlorophenyl)(phenyl)methanone (CAS 5162-03-8) is a benzophenone derivative used as an organic reagent and pharmaceutical intermediate in chemical synthesis and life-science research. It is supplied as a high-purity solid and commonly used as a building block in small-molecule preparation.
- High purity suitable for synthesis and analytical work.
- Functions as a pharmaceutical intermediate and reagent.
- Benzophenone scaffold with 2-chloro substitution for diverse transformations.
- Available in multiple laboratory package sizes for scalable work.
- Molecular formula C13H9ClO; molecular weight 216.66 g/mol.