Cresols
Medchemexpress LLC Pomalidomide-amido-PEG3-C2-NH2 | 2328070-52-4 | 99.5% | 100 MG
Pomalidomide-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It incorporates a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is for research use only and can be used to synthesize BI-3663, which degrades focal adhesion tyrosine kinase (PTK2).
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates pomalidomide-based cereblon ligand
- Features a 3-unit PEG linker
- Used in PROTAC technology
- Can be used to synthesize BI-3663
- Applicable in degrading PTK2 in hepatocellular carcinoma cell lines
Medchemexpress LLC BSJ-04-122 | 2513289-74-0 | C15H12ClN5O | 1 ML
BSJ-04-122 is a covalent MKK4/7 dual inhibitor. It inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. It can be used for cancer research.
- Covalent MKK4/7 dual inhibitor
- Inhibits MKK4 with IC50 of 4 nM
- Inhibits MKK7 with IC50 of 181 nM
- Useful for cancer research
Medchemexpress LLC Hyaluronan-binding peptide, biotin labeled TFA | 2012.25 (free base) | 5 MG
Hyaluronan-binding peptide, biotin labeled TFA is a biologically active peptide. This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan found in the extracellular matrix and on cell surfaces. HA plays roles in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
- Biologically active peptide
- Biotinylated through a C-terminal GGGSK linker
- Blocks HA binding to CD44 receptors
- Inhibits T cell proliferation