Cresols
Sigma Organic Chemistry STABILIZER - P | 10G
STABILIZER - P, 10G
About This Item:
UNSPSC Code: 12352200
Storage: COOLER/REFRIGERATED
Sigma Organic Chemistry Poly(acrylonitrile-co-methyl acrylate) | 10G | 24968-79-4 | MFCD00284236
Poly(acrylonitrile-co-methyl acrylate), 10G
About This Item:
Storage: room temp
Selleck Chemical LLC 2OH-BNPP1 S3522-5mg
2OH-BNPP1 is an inhibitor of the kinase activity of BUB1 (budding uninhibited by benzimidazoles-1 BUB1 Mitotic Checkpoint Serine/Threonine Kinase) that can be used for the treatment of cancer
Apexbio Technology LLC EZ Cap Mouse CD137 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse CD137 mRNA encodes CD137P(4-1BB) mainly expressed on activated T cells natural killer (NK) cells and dendritic cells The ligand for CD137 is 4-1BBL primarily expressed on antigen-presenting cells Activation of CD137 enhances T-cell proliferation and survival and promotes the secretion of cytokines such as IFN- and IL-2 thereby strengthening immune responses Activating CD137 can enhance anti-tumor immune responses CD137 signaling pathways play complex roles in autoimmune diseases and transplant rejection EZ Cap Mouse CD137 mRNA (m1 HA tag) supplied at 1 mg/mL encodes mouse-derived CD137 cytokine fused to HA tag facilitating subsequent protein expression detection It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse GM-CSF mRNA (m1Ψ) 1mg (1mg/mL)
GM-CSF mRNA encodes Granulocyte-Macrophage Colony-Stimulating Factor (CSF) produced by T cells macrophages endothelial cells and fibroblasts It stimulates the differentiation of hematopoietic stem cells in bone marrow into granulocytes and macrophages thereby enhancing the body s immune response capability GM-CSF not only promotes leukocyte production but also enhances their functions such as improving phagocytosis and antigen presentation abilities Clinically GM-CSF is used to treat certain types of leukopenia and serves as an adjuvant in cancer immunotherapy EZ Cap Mouse GM-CSF mRNA (m1 ) is provided at 1 mg/mL It expresses mouse-derived GM-CSF cytokine It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-12 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse CD137 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse CD137 mRNA encodes CD137P(4-1BB) mainly expressed on activated T cells natural killer (NK) cells and dendritic cells The ligand for CD137 is 4-1BBL primarily expressed on antigen-presenting cells Activation of CD137 enhances T-cell proliferation and survival and promotes the secretion of cytokines such as IFN- and IL-2 thereby strengthening immune responses Activating CD137 can enhance anti-tumor immune responses CD137 signaling pathways play complex roles in autoimmune diseases and transplant rejection EZ Cap Mouse CD137 mRNA (m1 HA tag) supplied at 1 mg/mL encodes mouse-derived CD137 cytokine fused to HA tag facilitating subsequent protein expression detection It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse IL-23α mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse IL-23 mRNA encodes a subunit of interleukin-23 (IL-23) IL-23 has two subunits p19 (IL-23 ) and p40 IL-23 binds p40 to form a functional cytokine promoting differentiation and maintenance of Th17 cells which are essential in anti-microbial defense and autoimmune diseases Dysregulated expression of IL-23 is associated with multiple inflammatory diseases such as psoriasis Crohn s disease and multiple sclerosis IL-23 and its subunit IL-23 are therapeutic targets for these diseases and numerous biologics have been developed to inhibit their activity EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vi
Selleck Chemical LLC Pifithrin-μ S2930-10mM/1mL
Pifithrin- (NSC 303580 PFT 2-Phenylethynesulfonamide) is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2 and also inhibits HSP70 function and autophagy
Selleck Chemical LLC p-Anisaldehyde S5086-25ul
p-Anisaldehyde (4-Methoxybenzaldehyde Anisaldehyde Anisic aldehyde P-Methoxybenzaldehyde 4-Anisaldehyde) an extract from Pimpinella anisum seeds exhibits antifungal activity against a number of yeast and mold strains in laboratory media fruit purees and fruit juices
Selleck Chemical LLC Rebaudioside M S3282-1mg
Rebaudioside M isolated from Stevia rebaudiana Bertoni is a natural non-caloric potential sweetener in food and beverage products
Selleck Chemical LLC Pifithrin-μ S2930-50mg
Pifithrin- (NSC 303580 PFT 2-Phenylethynesulfonamide) is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2 and also inhibits HSP70 function and autophagy
Chem-Impex International, Inc. 4-Chloro-2-methylphenol | MFCD00002321 | 5G
4-Chloro-2-methylphenol, MFCD00002321, 5G