Cresols
Medchemexpress LLC M-CSF Human CHO 500ug
Recombinant human M-CSF (CSF-1), produced in CHO cells and supplied as a tag-free, lyophilized protein, is a glycosylated, disulfide-linked homodimer that promotes proliferation, differentiation, and polarization of monocyte-macrophage lineage cells. It is suitable for macrophage and osteoclast differentiation assays, signaling studies, and functional bioassays requiring biologically active human M-CSF.
- CHO-expressed with mammalian glycosylation for native activity.
- Tag free to avoid interference in binding and bioassays.
- Purity greater than 95% by reducing SDS-PAGE.
- Apparent molecular weight reflects glycosylation (18-22 kDa reduced).
- Lyophilized formulation for extended storage and convenient reconstitution.
- Datasheet and certificate of analysis available for quality assurance.
Cambridge Isotope Laboratories 4-Isopropyl-3-methylphenol (isopropyl-13C3 99%) 100 ug/mL in methanol 1 2 mL
4-Isopropyl-3-methylphenol (isopropyl-13C3 99%) 100 ug/mL in methanol 1 2 mL
BIOHIPPO TetOn h/m P53-sh-Puro
TetOn h/m P53-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Cambridge Isotope Laboratories 2 4-Dimethylphenol (ring-D3 98%) 0 25 g
2 4-Dimethylphenol (ring-D3 98%) 0 25 g
Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-12 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cayman Chemical StemRegenin 1 Other Receptor M
A purine derivative that reversibly antagonizes aryl hydrocarbon receptor signaling (IC50 = 127 nM in CD34+ cells); induces a 50-fold increase in human embryonic stem cells expressing CD34 (EC50 = 120 nM) and a 17-fold increase in stem cells that retain the ability to engraft immunodeficient mice
Cambridge Isotope Laboratories 5-Isopropyl-2-methylphenol (isopropyl-13C3 99%) 1 mg/mL in methanol 1 2 mL
5-Isopropyl-2-methylphenol (isopropyl-13C3 99%) 1 mg/mL in methanol 1 2 mL
Medchemexpress LLC M-PEG2-acid | 149577-05-9 | 5 G
m-PEG2-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are molecules that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These molecules typically consist of two different ligands connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system for selective degradation of target proteins
- Intended for research use only
Medchemexpress LLC m-PEG2-acid | 149577-05-9 | >98% | 1 G
m-PEG2-acid is a polyethylene glycol (PEG)-based PROTAC linker. It is primarily used in the synthesis of Proteolysis-Targeting Chimeras (PROTACs), which are molecules designed to exploit the intracellular ubiquitin-proteasome system. PROTACs achieve selective degradation of target proteins by linking them to an E3 ubiquitin ligase.
- PEG-based PROTAC linker
- Facilitates the synthesis of PROTACs
- Molecular weight of 148.16
- Chemical formula C6H12O4
- Appears as a colorless to light yellow liquid
- Density of 1.098 ±0.06 g/cm³
- Storage for pure form: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
BIOHIPPO h/m GLUT1-sh-BSD
h/m GLUT1-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m GLUT1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse Glucose transporter 1 (GLUT1/GLUT-1/SLC2A1) The shRNA has been validated to meet or exceed 70% GLUT1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Apexbio Technology LLC Cytochrome c fragment (93-108) 1mg
Cytochrome c fragment 93-108 is a peptide derived from cytochrome c a mitochondrial protein involved in apoptosis It is designed to interact with apoptotic protease activating factor-1 (Apaf-1) thereby promoting the assembly of the Apaf-1/caspase-9 apoptosome complex and regulating the caspase activation pathway Cytochrome c fragment 93-108 exerts its biological activity primarily through activation of the caspase cascade specifically the activation of caspase-9 and subsequent caspase-3 Based on these pharmacological properties cytochrome c fragment 93-108 holds research potential in studies of apoptosis-related signaling networks caspase activation pathways and drug screening targeting apoptosis regulators
Medchemexpress LLC M-PEG17-acid | 2346581-96-0 | 98.5% | C36H72O19 | 100 MG
m-PEG17-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules employ the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system.
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cayman Chemical EA4 Fatty Acids and Derivative
An inhibitor of PLA2 from red blood cells (Ki = 130 µM); inhibits the ionophore-induced arachidonic acid release from human and bovine RBCs; induces mRNA expression and increases protein levels of CYP1A1 in murine hepatoma Hepa-1c1c7 cells; modulates CYP1A1 and CYP1B1 expression in MCF-7, Hep-G2, and HL-60 cells
Medchemexpress LLC Animal-free IL-13 protein, mouse (His) | 10UG
Recombinant mouse interleukin-13 (IL-13) produced under animal-free conditions and supplied with a polyhistidine tag for purification and detection. The protein is intended for research use in in vitro assays, including cell signaling and cytokine stimulation studies. SDS/PAGE data indicate an approximate molecular weight of 11 kDa. Pack sizes are suitable for assay-scale experiments.
- Animal-free preparation reduces risk of animal-derived contaminants.
- His tag enables efficient purification and detection.
- Suitable for in vitro cell culture and cytokine stimulation assays.
- Approximate molecular weight 11.0 kDa (SDS-PAGE) aids experimental planning.
- Pack sizes appropriate for assay-scale experiments.