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Filtered Search Results
Medchemexpress LLC Apolipoprotein M (APOM) | >90.0% | 100 UG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant human apolipoprotein M supplied as a lyophilized, His-tagged protein produced in HEK293 cells. The product represents full-length isoform-1 (residues M1-N188), is >90% pure by reducing SDS-PAGE, and is lyophilized from PBS pH 7.4 for stable storage. Intended for research use in biochemical and structural studies.
- Recombinant human apolipoprotein M expressed in HEK293 cells.
- C-terminal 6xHis tag for detection and purification.
- Full-length isoform-1 (residues M1-N188).
- Greater than 90.0% purity by reducing SDS-PAGE.
- Lyophilized formulation for enhanced stability.
- Lyophilized from PBS, pH 7.4 (0.22 μm filtered) for consistent reconstitution.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (1S,2S)-2-((R)-1-phenylethylamino)cyclohexanol | 98361-56-9 | 98.0% | C14H21NO | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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(1S,2S)-2-((R)-1-Phenylethylamino)cyclohexanol is a drug intermediate for the synthesis of various active compounds. It is supplied as a solid and is stable under recommended storage conditions, used primarily as a laboratory chemical in the manufacture of substances.
- Used as a drug intermediate for synthesis of various active compounds
- Stable under recommended storage conditions
- For research use only
- Must be handled by suitably qualified experienced scientists
- Available as a solid
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Interleukin-31 (mouse) | >95.0% | 10UG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Animal-free IL-31 protein is a recombinant, His-tagged mouse interleukin-31 produced in Escherichia coli and supplied lyophilized. It corresponds to residues T24-C163 (accession Q6EAL8), has a predicted molecular weight of 16.6 kDa (observed ≈17.0 kDa), and is >95% pure by reducing SDS-PAGE. Formulated in PBS (pH 7.4) with trehalose, it is intended for research use and stored at -20°C.
- Recombinant His-tagged mouse interleukin-31
- Expressed in Escherichia coli
- Sequence range T24-C163 (accession Q6EAL8)
- Predicted 16.6 kDa; observed ≈17.0 kDa
- Purity greater than 95% by reducing SDS-PAGE
- Lyophilized formulation in PBS pH 7.4 with trehalose
- Store at -20°C; freeze aliquots for long-term storage
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO h/m P53-sh-RFP-Puro
h/m P53-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cambridge Isotope Laboratories 1 2 3 7 8 9-HexaCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 7 8 9-HexaCDD (unlabeled) 25 ng/mL in nonane 0 2 mL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ) 100ug (1mg/mL)
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 ) is provided at 1 mg/mL encoding mouse IL-12 cytokine It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC m-PEG9-acid | 2576495-35-5 | MFCD27977514 | 98.0% | C20H40O11 | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG9-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds consist of two ligands connected by a linker, one for an E3 ubiquitin ligase and the other for a target protein, enabling the selective degradation of target proteins via the intracellular ubiquitin-proteasome system. This product is a colorless to light yellow liquid, with a molecular formula of C20H40O11 and a molecular weight of 456.53, intended for laboratory use only.
- Peg-based protac linker
- Used in the synthesis of protacs
- Enables selective degradation of target proteins
- Utilizes the intracellular ubiquitin-proteasome system
- For laboratory and research use only
- Colorless to light yellow liquid
- Purity of 98.0%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO h/m USP20 shRNA Set GFP Puro
h/m USP20 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated human/mouse USP20 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse ubiquitin specific peptidase 20 (USP20) The shRNA has been validated to meet or exceed 70% USP20 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 443-90-3 | 2-Fluoro-6-methylphenol | Combi-Blocks | MFCD12026463 | 126.130 | C7H7FO | 96.000 | Cc1cccc(F)c1O | 1g | 267183793
2-Fluoro-6-methylphenol | Combi-Blocks | 443-90-3 | MFCD12026463 | 126.130 | C7H7FO | 96.000 | Cc1cccc(F)c1O | 1g | 267183793
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cambridge Isotope Laboratories 1 8-DiCN (PCN-9) (unlabeled) 100 ug/mL in nonane 1 mL
1 8-DiCN (PCN-9) (unlabeled) 100 ug/mL in nonane 1 mL
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG17-acid | 2346581-96-0 | 98.5% | C36H72O19 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG17-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Kynureninase (KYNU), recombinant mouse, C-terminal His tag | 9024-78-6 | 90.0% | 100 UG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Recombinant mouse KYNU (kynureninase) is a pyridoxal phosphate-dependent enzyme produced in Sf9 insect cells with a C-terminal His tag. It catalyzes conversion of L-kynurenine and L-3-hydroxykynurenine to anthranilic acid and 3-hydroxyanthranilic acid and shows preference for the L-3-hydroxy substrate.
- Recombinant mouse enzyme expressed in Sf9 insect cells.
- C-terminal His tag for affinity purification.
- Molecular weight approximately 47 kDa.
- Purity 90.0%.
- Available in 10 μg, 50 μg, and 100 μg pack sizes.
- Store at -80°C; stable for 1 year under recommended storage.
- Catalyzes conversion of L-kynurenine and L-3-hydroxykynurenine; prefers the L-3-hydroxy form.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO h/m NRP1-sh-Puro
h/m NRP1-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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BIOHIPPO h/m GLUT1-sh-RFP-BSD
h/m GLUT1-sh-RFP-BSD shRNA lentiviral vector expressing RFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m GLUT1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse Glucose transporter 1 (GLUT1/GLUT-1/SLC2A1) The shRNA has been validated to meet or exceed 70% GLUT1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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