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Filtered Search Results
Medchemexpress LLC 5-fluorouridine 5'-phosphate | 796-66-7 | MFCD30532520 | 98.6% | 342.17 g·mol⁻¹ | C9H12FN2O9P | 100mg
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5-Fluorouridine 5 -phosphate is an ODCase (orotidine-5 -monophosphate decarboxylase) inhibitor with a Ki value of 98 M for human ODCase and a Ki value of 645 M for Methanobacterium ODCase 5-Fluorouridine 5 -phosphate exhibits inhibitory activity against leukemia and lymphoma cell lines and can be used in cancer research [1]
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eMolecules Chem-Impex p-Anisaldehyde 1kg 490847548 33800 0 000 123-11-5 MFCD00003385 136 150 C8H8O2
Chem-Impex p-Anisaldehyde 1kg 490847548 33800 0 000 123-11-5 MFCD00003385 136 150 C8H8O2
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Chemscene ChemScene | 2-Bromo-3,5-dimethylphenol | 5G | CS-0061219 | 0.97 | 125237-08-3| MFCD22058629 | 201.063
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ChemScene | 2-Bromo-3,5-dimethylphenol | 5G | CS-0061219 | 0.97 | 125237-08-3| MFCD22058629 | 201.063
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Medchemexpress LLC 1H-Pyrrole-2,5-dione, 1-(4-methylphenyl)- | 1631-28-3 | ≥98.0% | 25 MG
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p-Tolylmaleimide is a naphthalimide derivative that exhibits cytotoxic effects on cancer cells. This compound can arrest the cell cycle of human acute myeloid leukemia cells in the sub-G0/G1 phase and induce apoptosis. It appears as a light yellow to yellow solid, with a molecular weight of 187.19 and formula C11H9NO2.
- Has cytotoxic effects on cancer cells
- Arrests cell cycle in sub-G0/G1 phase
- Induces apoptosis
- Inhibits human acute myeloid leukemia K562 cells
- Inhibits human acute myeloid leukemia Jurkat cells
- Soluble in DMSO at ≥ 100 mg/mL
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TARGETMOL CHEMICALS INC TOXOFLAVIN 10MG
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Also available in 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/(beta)-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A. purity: 99%
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BIOHIPPO h/m IGFBP2 shRNA Set GFP Puro
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h/m IGFBP2 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated IGFBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse insulin like growth factor binding protein 2 (IGFBP2) The shRNA has been validated to meet or exceed 70% IGFBP2 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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BIOHIPPO h/m P53-sh-RFP-Puro
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h/m P53-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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BIOHIPPO h/m GLUT1-sh-GFP-BSD
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h/m GLUT1-sh-GFP-BSD shRNA lentiviral vector expressing GFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m GLUT1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse Glucose transporter 1 (GLUT1/GLUT-1/SLC2A1) The shRNA has been validated to meet or exceed 70% GLUT1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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BIOHIPPO h/m ACSL4-sh-BSD
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h/m ACSL4-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Medchemexpress LLC Pomalidomide-amido-PEG3-C2-NH2 | 2328070-52-4 | 99.55% | 50 MG
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Pomalidomide-amido-PEG3-C2-NH2 is a high-purity, synthesized E3 ligase ligand-linker conjugate designed for research applications in PROTAC technology. This compound incorporates a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. It can be utilized in the synthesis of BI-3663, a compound known to degrade focal adhesion tyrosine kinase (PTK2) in various cell lines.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Features a 3-unit PEG linker
- Used in PROTAC technology
- For research use only
- Can be used to synthesize BI-3663
- Degrades focal adhesion tyrosine kinase (PTK2)
- Purity of 99.55%
- Solid appearance, off-white to light yellow color
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Medchemexpress LLC 3-(2-Pyridyldithio)propanoic Acid | 68617-64-1 | 99.5% | 500 MG
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3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. It is intended for research use only and not sold to patients. This compound has a molecular weight of 215.29 and the formula C8H9NO2S2. It appears as a white to off-white solid.
- Alkyl chain-based linker
- Used in the synthesis of PROTACs
- PROTACs exploit the ubiquitin-proteasome system
- Selectively degrades target proteins
- White to off-white solid appearance
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Medchemexpress LLC 6,7-Dimethoxy-2-(2-phenylethyl)chromone | 84294-87-1 | 5 MG
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6,7-Dimethoxy-2-(2-phenylethyl)chromone is a natural compound for research use only.
- Not sold to patients
- Purity 98.99%
- Molecular weight 310.34
- Molecular formula C19H18O4
- Appearance solid
- Color white to off-white
- Stable under recommended storage conditions
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Medchemexpress LLC o-Cresolphthalein complexone | 2411-89-4 | 5 G
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o-Cresolphthalein complexone | 2411-89-4 | 5 G
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Medchemexpress LLC m-PEG-azide | 98.0% | 500 MG
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m-PEG-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with Azide group
- Enables CuAAc reactions with Alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
- Utilizes ubiquitin-proteasome system for selective protein degradation
- White to off-white solid
- For research use only
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eMolecules Advanced ChemBlocks - In Stock 3-Fluorobicyclo[1 1 1]pentan-1-amine hydrochloride 250mg 381428201 L22201 97 000 1826900-79-1 MFCD28963742 137 580 C5H9ClFN
Advanced ChemBlocks - In Stock 3-Fluorobicyclo[1 1 1]pentan-1-amine hydrochloride 250mg 381428201 L22201 97 000 1826900-79-1 MFCD28963742 137 580 C5H9ClFN
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